DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7402 and Arsg

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001348904.1	Gene:	Arsg / 74008	MGIID:	1921258	Length:	525	Species:	Mus musculus

Alignment Length:	561	Identity:	146/561 - (26%)
Similarity:	218/561 - (38%)	Gaps:	129/561 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VLLVVSSILSLAY--------GSGYSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGI 64
            ||||..:.....|        |...:.:|||||||.||||..|:..:.:....|.|:|.:|..|:
Mouse     8 VLLVGMAFSGFFYPLVDFSISGKTRAPQPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGM 72

  Fly    65 -LLNKHYVPNLCTPSRATLLTGKYPIHTGMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVG 128
             .::.|...:.|:||||:||||:..:..|:.|...:| ...|||..|..:.|:.|..||.|.::|
Mouse    73 RFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVT-SVGGLPVNETTLAEVLRQEGYVTAMIG 136

  Fly   129 KWHLGFWRKDLTPTMRGFDHHFG--YYN--------GYIDYYDHQVRMLDRNYSAGLDFRRDLEP 183
            |||||. .....|..||||::||  |.|        ||             ||.       ....
Mouse   137 KWHLGH-HGSYHPNFRGFDYYFGIPYSNDMGCTDAPGY-------------NYP-------PCPA 180

  Fly   184 CPEANGTY------------------------------ATEAFTSEAKRIIEQHDKS-KP--LFM 215
            ||:.:|.:                              ..:.:...|...|||...| :|  |::
Mouse   181 CPQRDGLWRNPGRDCYTDVALPLYENLNIVEQPVNLSGLAQKYAERAVEFIEQASTSGRPFLLYV 245

  Fly   216 VLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRT-YAGMISSLDKSVAQTIGALKDNGMLNNS 279
            .|:|:.|       |:...       |.:..|:|:: |...:..:|..|.| |....|:....|:
Mouse   246 GLAHMHV-------PLSVT-------PPLAHPQRQSLYRASLREMDSLVGQ-IKDKVDHVARENT 295

  Fly   280 IILLYSDNGAPTIGIHSNAGSNYPYRG----------QKESPWEGGIRSAGALWSPLLKERGYVS 334
            ::....||| |.......|||..|:.|          .|::.||||.|.....:.|........|
Mouse   296 LLWFTGDNG-PWAQKCELAGSVGPFFGLWQTHQGGSPTKQTTWEGGHRVPALAYWPGRVPANVTS 359

  Fly   335 NQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFG--------- 390
            ...:..:|..||:...||.|||.:...||.::..:|.|..:...|.:.|......|
Mouse   360 TALLSLLDIFPTVIALAGASLPPNRKFDGRDVSEVLFGKSQMGHRVLFHPNSGAAGEYGALQTVR 424

  Fly   391 ---YSS-YMRDTLKYVNGSSFKGRYDQWLGELETNEDD------PL--GESYEQHVLASDVQSLL 443
               |.: |:....|..:||  .|.....:..|..|.:|      ||  |....|.||....::|
Mouse   425 LNHYKAFYITGGAKACDGS--VGPEQHHVAPLIFNLEDAADEGMPLQKGSPEYQEVLQQVTRAL- 486

  Fly   444 GNRGLTKDRIRQMRSEATETCPP--IEGQNPLESHFKCEPL 482
              ..:.:|......|.|..|..|  |...||.::..:|:|:
Mouse   487 --ADVLQDIADDNSSRADYTQDPSVIPCCNPYQTTCRCQPV 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	131/509 (26%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	128/483 (27%)
Arsg	NP_001348904.1	ARSG	35..469	CDD:293780	124/473 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740