DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7402 and Sulf2

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001239508.1	Gene:	Sulf2 / 72043	MGIID:	1919293	Length:	908	Species:	Mus musculus

Alignment Length:	554	Identity:	113/554 - (20%)
Similarity:	204/554 - (36%)	Gaps:	155/554 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVVSSILSLAYGSG----------------YSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDA 58
            |:.:::|||..||.                .:.:|||:::|.||   .||.. ||.|::......
Mouse    43 LLSTALLSLLAGSSAFLSHPRLKGRFQRDRRNIRPNIILVLTDD---QDVEL-GSMQVMNKTRRI 103

  Fly    59 LAYNGI-LLNKHYVPNLCTPSRATLLTGKYPIHTGMQHFVIITDE-----PWGLPQRERLMPEIF 117
            :...|. .:|......:|.|||:::||||| :|   .|.....:|     .|......|......
Mouse   104 MEQGGAHFINAFVTTPMCCPSRSSILTGKY-VH---NHNTYTNNENCSSPSWQAQHESRTFAVYL 164

  Fly   118 RDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHFGYYNG-YID--------------YYDHQVRML 167
            ...||.|...||                   :...||| |:.              :|::.:...
Mouse   165 NSTGYRTAFFGK-------------------YLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRN 210

  Fly   168 DRNYSAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIEQHDK---SKPLFMVLSHLAVHTGNEDS 229
            ......|.|:..|          |.|:..|:::........|   .:|:.||:||.|.| |.|||
Mouse   211 GVKEKHGSDYSTD----------YLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPH-GPEDS 264

  Fly   230 PMQ------------------APEEE---VAKFPHIRDPKRRTYAGMIS--------SLDKSVAQ 265
            ..|                  ||..:   :.::.....|....:..|:.        |:|.|:..
Mouse   265 APQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMET 329

  Fly   266 TIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKER 330
            ....|.:.|.|:|:.||..:|:|       .:.|.....:| |..|:|..||....:..|.: |.
Mouse   330 IYDMLVETGELDNTYILYTADHG-------YHIGQFGLVKG-KSMPYEFDIRVPFYVRGPNV-EA 385

  Fly   331 GYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFGY-SSY 394
            |.::...:..:|..||:...||:.:|.|  :||.::..:|   :..:|....|:..::..: .|:
Mouse   386 GSLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLL---DSERPVNRFHLKKKLRVWRDSF 445

  Fly   395 MRDTLKYVN---GSSFKGRYDQWLGELETNED-----------DPLGESYEQHVLASDVQSLL-- 443
            :.:..|.::   |.....:.:.:|.:.:..:|           :.||:.::   ...|....|
Mouse   446 LVERGKLLHKREGDKVNAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQ---CVEDASGTLKL 507

  Fly   444 -------------GNRGLTKDRIRQMRSEATETC 464
                         |:|.|: :.:.:...:::|.|
Mouse   508 HKCKGPMRFGGGGGSRALS-NLVPKYDGQSSEAC 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	105/516 (20%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	100/475 (21%)
Sulf2	NP_001239508.1	AslA	76..>420	CDD:225661	90/392 (23%)
		G6S	76..418	CDD:293766	90/390 (23%)
		DUF3740	573..699	CDD:289325
		ALP_like	<787..836	CDD:304875
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847537
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740