DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7402 and ids

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001073537.1	Gene:	ids / 559959	ZFINID:	ZDB-GENE-061215-37	Length:	561	Species:	Danio rerio

Alignment Length:	520	Identity:	119/520 - (22%)
Similarity:	196/520 - (37%)	Gaps:	147/520 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 NIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPN-LCTPSRATLLTGKYPIHTG 92
            |::.::.||: ...:..:....:.:||||.||...::.:..|... :|.|||.:.||.:.|..|.
Zfish    32 NVLYLIADDL-RPTLGCYSDPVVKSPNIDQLASLSVVFHNAYAQQAVCGPSRVSFLTSRRPDTTK 95

  Fly    93 MQHFVIITDEPWGL-PQRERLMPEIFRDAGYSTHLVGK-WHLGFWRKDLTPTMRGFDHHFGY-YN 154
            :..|    :..|.: ......:|:.|:..||:|..||| :|.|.          ..:|...| |:
Zfish    96 LYDF----NSYWRVHAGNYTTLPQYFKSNGYTTLSVGKVFHPGI----------ASNHSDDYPYS 146

  Fly   155 GYIDYY-----DHQVRMLDRNYSAGLDFRRDLEPCPEAN------GTYATEAFTSEAKRIIEQHD 208
            ..:..|     :::.|.:.::....|....   .|| .|      ||......|.||.|::....
Zfish   147 WSVPPYHPPSFEYEKRKVCKDKDGTLHSNL---LCP-VNVSEMPLGTLPDMENTEEAIRLLRSMK 207

  Fly   209 KS-KPLFMVLSHLAVH--------------------TGNEDSPMQAPE------------EEV-- 238
            .| ||.|:.:.....|                    ..:.|.|.:.|:            |:|
Zfish   208 GSQKPFFLSVGFYKPHIPFRIPQEYLKLYPIENMTLAPDPDVPKKLPDVAYNPWTDIRKREDVQA 272

  Fly   239 --AKFPHIRDPK------RRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIH 295
              ..||:...||      |:.|...:|.:|..|.:.:..|.|.|:..|:|::|.||:|. ::|.|
Zfish   273 LNLSFPYGPIPKDFQLRIRQHYFASVSYVDAQVGKILQTLDDVGLAKNTIVVLSSDHGW-SLGEH 336

  Fly   296 SNAGSNYPYRGQKESP---WEGGIRS----AGALWSPLL------KE---RGYVSNQAIHAVDWL 344
            ........:......|   ::.|:.|    .||...|.:      :|   :|.:.|..:..:|..
Zfish   337 GEWAKYSNFDVATRVPLMVYKAGVSSRRSRPGAKTFPFIDVFQDTREHFGKGKIVNSVVELLDVF 401

  Fly   345 PTLAGAAGV---------SLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFGYSSYMR--DT 398
            ||||..||:         |...||..:|.||..::   ..||     |:..|.:.:|.|.|  |:
Zfish   402 PTLANLAGLPSVHHCPSPSFKMDLCTEGSNLANLI---RNPK-----HLNREAYSFSQYPRPSDS 458

  Fly   399 LK-----------YVNGSSFKG---RYDQWLGELETNEDDPL-----------GESYEQHVLASD 438
            ::           .:.|.|.:.   ||..|:|      .|||           ||.|   :|..|
Zfish   459 IQENSDLPNLADIRIMGYSIRSNDYRYTLWVG------FDPLHCKPNMTEIHAGELY---ILTED 514

Fly 439 438
Zfish 515 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	119/520 (23%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	117/516 (23%)
ids	NP_001073537.1	iduronate-2-sulfatase	29..527	CDD:293754	119/520 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810