Protein Alignment CG7402 and ARSF

DIOPT Version :10

• Sequence 1: NP_649023.1
• Gene: CG7402 / 39994
• FlyBaseID: FBgn0036768
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_011543824.1
• Gene: ARSF / 416
• HGNCID: 721
• Length: 607
• Species: Homo sapiens
• Alignment Length: 593
• Identity: 148/593 - (24%)
• Similarity: 230/593 - (38%)
• Gaps: 163/593 - (27%)

  Fly    24 YSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHY-VPNLCTPSRATLLTGKY 87
            :..|||||:|::||:|:.|:..:|::.:.||:||.||..|:.|.:|. ..:||:|||:..|||:|
Human    43 HDDKPNIVLIMVDDLGIGDLGCYGNDTMRTPHIDRLAREGVRLTQHISAASLCSPSRSAFLTGRY 107

  Fly    88 PIHTGM---------QHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLTPTM 143
            ||.:||         |:..:    |.|||..|..:..:.:..||||.|:||||.|     |....
Human   108 PIRSGMVSSGNRRVIQNLAV----PAGLPLNETTLAALLKKQGYSTGLIGKWHQG-----LNCDS 163

  Fly   144 RGFDHHFGYYNGYIDYYDHQVRMLD-------RNYSAGLD------------------------- 176
            |....|..|..|:..||.....::|       ||.....:
Human   164 RSDQCHHPYNYGFDYYYGMPFTLVDSCWPDPSRNTELAFESQLWLCVQLVAIAILTLTFGKLSGW 228

  Fly   177 ----------------------FRRDLEP----CPEANGTYATE----------AFTSEAKRIIE 205
                                  |.....|    |....|...||          ....||...:|
Human   229 VSVPWLLIFSMILFIFLLGYAWFSSHTSPLYWDCLLMRGHEITEQPMKAERAGSIMVKEAISFLE 293

  Fly   206 QHDKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGAL 270
            :|.| :...:..|.|.|||     |:...::......|      ..|...:..:|..|.:.:.|:
Human   294 RHSK-ETFLLFFSFLHVHT-----PLPTTDDFTGTSKH------GLYGDNVEEMDSMVGKILDAI 346

  Fly   271 KDNGMLNNSIILLYSDNGAPTIGIHSNA---GSNYPYRGQK-ESPWEGGIRSAGALWSPLLKERG 331
            .|.|:.||:::...||:|........:|   |.|..|:|.| ...||||||..|.:..|.....|
Human   347 DDFGLRNNTLVYFTSDHGGHLEARRGHAQLGGWNGIYKGGKGMGGWEGGIRVPGIVRWPGKVPAG 411

  Fly   332 YVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFGY-SSYM 395
            .:..:....:|.|||:|..:|.|||||..:||.:|.|:|.||........:      |.| .||:
Human   412 RLIKEPTSLMDILPTVASVSGGSLPQDRVIDGRDLMPLLQGNVRHSEHEFL------FHYCGSYL 470

  Fly   396 RDTLKYVNGSSFKGRYDQWLGELETNEDDPLGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEA 460
            ...              :|:.:      |..|..::.|.:....|
Human   471 HAV--------------RWIPK------DDSGSVWKAHYVTPVFQ-------------------- 495

  Fly   461 TETCPPIEGQNPLESHFKC--EPL---KAPCFFDLAKDPCERYNLA----QMYPLQLQQLADELE 516
                ||..|...:.|..:|  |.:   ..|..|||::||.|...|.    .::...::::|:.|:
Human   496 ----PPASGGCYVTSLCRCFGEQVTYHNPPLLFDLSRDPSESTPLTPATEPLHDFVIKKVANALK 556

  Fly   517 QIRKTAIP 524
            :.::|.:|
Human   557 EHQETIVP 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	4-S	28..436	CDD:293753	128/490 (26%)
ARSF	XP_011543824.1	ALP_like	46..570	CDD:474031	148/590 (25%)