Protein Alignment CG7402 and ARSL

DIOPT Version :10

• Sequence 1: NP_649023.1
• Gene: CG7402 / 39994
• FlyBaseID: FBgn0036768
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001269557.1
• Gene: ARSL / 415
• HGNCID: 719
• Length: 614
• Species: Homo sapiens
• Alignment Length: 633
• Identity: 153/633 - (24%)
• Similarity: 235/633 - (37%)
• Gaps: 174/633 - (27%)

  Fly     8 VLLVVSSILSLAYGSGYSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHY-V 71
            :|.|:.|:...|.....:::|||::::.||:|:.|:..:|:|.:.|||||.||.:|:.|.:|. .
Human    43 MLAVLLSLAPSASSDISASRPNILLLMADDLGIGDIGCYGNNTMRTPNIDRLAEDGVKLTQHISA 107

  Fly    72 PNLCTPSRATLLTGKYPIHTGMQHFVIITDEPW-----GLPQRERLMPEIFRDAGYSTHLVGKWH 131
            .:|||||||..|||:||:.:||...:......|     |||..|....:|.::.||:|.|:||||
Human   108 ASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYATGLIGKWH 172

  Fly   132 LGFWRKDLT-----PTMRGFDHHFG---------------------------------------- 151
            ||...:..:     |...||||.:|
Human   173 LGLNCESASDHCHHPLHHGFDHFYGMPFSLMGDCARWELSEKRVNLEQKLNFLFQVLALVALTLV 237

  Fly   152 -----------------------------YYNGYIDYYDHQVRMLDRNYSAGLDFRRDLEPCPEA 187
                                         |:.|.:  ..|....|.||::.     .:...|.:.
Human   238 AGKLTHLIPVSWMPVIWSALSAVLLLASSYFVGAL--IVHADCFLMRNHTI-----TEQPMCFQR 295

  Fly   188 NGTYATEAFTSEAKRIIEQHDKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTY 252
            ......:...|..||     :|..|..:.:|.|.||.     |:...|..:.|..|      ..|
Human   296 TTPLILQEVASFLKR-----NKHGPFLLFVSFLHVHI-----PLITMENFLGKSLH------GLY 344

  Fly   253 AGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAP---TIGIHSNAGSNYPYRGQK-ESPWE 313
            ...:..:|..|.:.:..|...|:.|:::|...||:|..   .:|.....|.|..|:|.| ...||
Human   345 GDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWE 409

  Fly   314 GGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKP 378
            ||||..|....|.:...|.|..:....:|..||:...||..:|||..:||.:|.|:|.|..:...
Human   410 GGIRVPGIFRWPGVLPAGRVIGEPTSLMDVFPTVVRLAGGEVPQDRVIDGQDLLPLLLGTAQHSD 474

  Fly   379 RTMIHVLDEVFGYSS--YMRDTLKYVNGSSFKGRYDQWLGELETNEDDP--LGESYEQHVLASDV 439
            ...:....|.|.:::  :.||            |...|.....|....|  .|..|.:.|
Human   475 HEFLMHYCERFLHAARWHQRD------------RGTMWKVHFVTPVFQPEGAGACYGRKV----- 522

  Fly   440 QSLLGNRGLTKDRIRQMRSEATETCPPIEGQNPLESHFKCEPLKAPCFFDLAKDPCERYNLAQMY 504
                                    ||.. |:..:..    :|   |..|||::||.|.:.|....
Human   523 ------------------------CPCF-GEKVVHH----DP---PLLFDLSRDPSETHILTPAS 555

  Fly   505 PLQLQQLADELEQI----RKTAIPSARVPHSDSRANPTFHNGN-WEWW 547
            .....|:.:.::|.    ::|..|   ||....|.      || |..|
Human   556 EPVFYQVMERVQQAVWEHQRTLSP---VPLQLDRL------GNIWRPW 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	4-S	28..436	CDD:293753	126/495 (25%)
ARSL	NP_001269557.1	ALP_like	62..585	CDD:474031	144/597 (24%)