Protein Alignment CG7402 and ARSD

DIOPT Version :9

• Sequence 1: NP_649023.1
• Gene: CG7402 / 39994
• FlyBaseID: FBgn0036768
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001660.2
• Gene: ARSD / 414
• HGNCID: 717
• Length: 593
• Species: Homo sapiens
• Alignment Length: 630
• Identity: 154/630 - (24%)
• Similarity: 224/630 - (35%)
• Gaps: 206/630 - (32%)

  Fly    27 KPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHY-VPNLCTPSRATLLTGKYPIH 90
            ||||::|:.||:|..|:..:|:|.:.|||||.||..|:.|.:|. ...|||||||..|||::...
Human    40 KPNILLIMADDLGTGDLGCYGNNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRAAFLTGRHSFR 104

  Fly    91 TGMQHFVIITDEPW-----GLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLTPTMRGFDH-H 149
            :||..........|     |||:.|.....|.:..||:|.|:||||.|     :....|| || |
Human   105 SGMDASNGYRALQWNAGSGGLPENETTFARILQQHGYATGLIGKWHQG-----VNCASRG-DHCH 163

  Fly   150 FGYYNGYIDYYDHQVRMLDRNYSAGLDFRRDLEP--CPEANGT---------------------- 190
            ....:|: ||:          |........|.:|  .||.:..
Human   164 HPLNHGF-DYF----------YGMPFTLTNDCDPGRPPEVDAALRAQLWGYTQFLALGILTLAAG 217

  Fly   191 ---------------------------YATEAFT----------------------------SEA 200
                                       |::..|.                            .||
Human   218 QTCGFFSVSARAVTGMAGVGCLFFISWYSSFGFVRRWNCILMRNHDVTEQPMVLEKTASLMLKEA 282

  Fly   201 KRIIEQHDKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQ 265
            ...||:| |..|..:.||.|.||.     |:......:.|..|      ..|...:..:|..:.:
Human   283 VSYIERH-KHGPFLLFLSLLHVHI-----PLVTTSAFLGKSQH------GLYGDNVEEMDWLIGK 335

  Fly   266 TIGALKDNGMLNNSIILLYSDNGAPTIGIHSNA--------GSNYPYRGQK-ESPWEGGIRSAGA 321
            .:.|::|||:.|::.....||:|.     |..|        |.|..|:|.| ...||||||..|.
Human   336 VLNAIEDNGLKNSTFTYFTSDHGG-----HLEARDGHSQLGGWNGIYKGGKGMGGWEGGIRVPGI 395

  Fly   322 LWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLD 386
            ...|.:...|.|..:....:|..||:....|..:|||..:||.:|.|:|.|.|.......:
Human   396 FHWPGVLPAGRVIGEPTSLMDVFPTVVQLVGGEVPQDRVIDGHSLVPLLQGAEARSAHEFL---- 456

  Fly   387 EVFGYSS--------YMRDTLKYVNGSSFKGRYDQWLGELETNEDDP--LGESYEQHVLASDVQS 441
              |.|..        :.:|     :||.:|..|       .|.:..|  .|..|
Human   457 --FHYCGQHLHAARWHQKD-----SGSVWKVHY-------TTPQFHPEGAGACY----------- 496

  Fly   442 LLGNRGLTKDRIRQMRSEATETCPPIEGQNPLESHFKCEPLKAPCFFDLAKDPCERYNLA----Q 502
               .||:               | |..|:. :..|      :.|..|||::||.|...|.    .
Human   497 ---GRGV---------------C-PCSGEG-VTHH------RPPLLFDLSRDPSEARPLTPDSEP 535

  Fly   503 MYPLQLQQLADELEQIRKTAIPSARVPHSDSRANPTFHNGNWEWW 547
            :|...:.::...:.:.|:|..|   ||...|.:|..     |:.|
Human   536 LYHAVIARVGAAVSEHRQTLSP---VPQQFSMSNIL-----WKPW 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	132/536 (25%)
		4-S	28..436	CDD:293753	129/512 (25%)
ARSD	NP_001660.2	ALP_like	40..563	CDD:304875	150/614 (24%)
		AslA	40..525	CDD:225661	142/573 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157195
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740