Protein Alignment CG7402 and STS

DIOPT Version :10

• Sequence 1: NP_649023.1
• Gene: CG7402 / 39994
• FlyBaseID: FBgn0036768
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001307679.1
• Gene: STS / 412
• HGNCID: 11425
• Length: 590
• Species: Homo sapiens
• Alignment Length: 616
• Identity: 154/616 - (25%)
• Similarity: 245/616 - (39%)
• Gaps: 174/616 - (28%)

  Fly    25 STKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPN-LCTPSRATLLTGKYP 88
            :::|||::::.||:|:.|...:|:..|.|||||.||..|:.|.:|...: |||||||..:||:||
Human    31 ASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTGRYP 95

  Fly    89 IHTGMQHF-----VIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLT-----PTM 143
            :.:||..:     .:.|....|||..|....::.:|.||||.|:||||||......|     |..
Human    96 VRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLH 160

  Fly   144 RGFDHHFG--------------------------------------------------------- 151
            .||::.:|
Human   161 HGFNYFYGISLTNLRDCKPGEGSVFTTGFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFS 225

  Fly   152 ----------YYNGYIDYYDHQVRMLDRNYSAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIEQ 206
                      .:.|::.|:......:.|||..      ..:|....|   .|:..|.||.:.|::
Human   226 LLFLAALILTLFLGFLHYFRPLNCFMMRNYEI------IQQPMSYDN---LTQRLTVEAAQFIQR 281

  Fly   207 HDKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGALK 271
            :.:: |..:|||:|.|||.     :.:.::...|..|      ..|...:..:|.||.|.:..|.
Human   282 NTET-PFLLVLSYLHVHTA-----LFSSKDFAGKSQH------GVYGDAVEEMDWSVGQILNLLD 334

  Fly   272 DNGMLNNSIILLYSDNGAPTIGIHS----NAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGY 332
            :..:.|:::|...||.||....:.|    :.|||..|:|.|.:.||||||..|.|..|.:.:.|.
Human   335 ELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKANNWEGGIRVPGILRWPRVIQAGQ 399

  Fly   333 VSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFGYSSYMRD 397
            ..::....:|..||:|..||..||:|..:||.:|.|:|.|..:......:      |.|.:...:
Human   400 KIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGRDLMPLLEGKSQRSDHEFL------FHYCNAYLN 458

  Fly   398 TLKY--VNGSSFKGRYDQWLGELETNEDDPLGES--YEQHVLASDVQSLLGNRGLTKDRIRQMRS 458
            .:::  .|.:|.      |.....|...:|:|.:  :..||...                  ..|
Human   459 AVRWHPQNSTSI------WKAFFFTPNFNPVGSNGCFATHVCFC------------------FGS 499

  Fly   459 EATETCPPIEGQNPLESHFKCEPLKAPCFFDLAKDPCERYNLA-----QMYPL--QLQQLADELE 516
            ..|...||:                   .||::|||.||..|.     :.|.:  .:|:.||...
Human   500 YVTHHDPPL-------------------LFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHT 545

  Fly   517 QIRKTAIPSARVPHSDSRANPTFHNGNWEWW 547
            |    .:|  .||...|     ::|..|:.|
Human   546 Q----TLP--EVPDQFS-----WNNFLWKPW 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	4-S	28..436	CDD:293753	130/493 (26%)
STS	NP_001307679.1	ES	33..557	CDD:293778	151/604 (25%)