Protein Alignment CG7402 and ARSB

DIOPT Version :10

• Sequence 1: NP_649023.1
• Gene: CG7402 / 39994
• FlyBaseID: FBgn0036768
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_000037.2
• Gene: ARSB / 411
• HGNCID: 714
• Length: 533
• Species: Homo sapiens
• Alignment Length: 551
• Identity: 202/551 - (36%)
• Similarity: 292/551 - (52%)
• Gaps: 50/551 - (9%)

  Fly     6 ILVLLVVSSILSLAYGSGYSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHY 70
            :|.||::..:.....|:|.|..|::|.:|.||:|.|||.|||| :|.||::||||..|:||:.:|
Human    23 VLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGS-RIRTPHLDALAAGGVLLDNYY 86

  Fly    71 VPNLCTPSRATLLTGKYPIHTGMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFW 135
            ...||||||:.||||:|.|.||:||.:|...:|..:|..|:|:|::.::|||:||:|||||||.:
Human    87 TQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMY 151

  Fly   136 RKDLTPTMRGFDHHFGYYNGYIDYYDHQ-VRMLDR-NYS-AGLDFRRDLEPCPEANGTYATEAFT 197
            ||:..||.||||.:|||..|..|||.|: ..::|. |.: ..||||...|........|:|..||
Human   152 RKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFT 216

  Fly   198 SEAKRIIEQHDKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKS 262
            ..|..:|..|...||||:.|:..:||     .|:|.|||.:..:..|:|..|..||||:|.:|::
Human   217 KRAIALITNHPPEKPLFLYLALQSVH-----EPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEA 276

  Fly   263 VAQTIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLL 327
            |.....|||.:|:.||::.:..:|||..|:.    .|:|:|.||:|.|.||||:|..|.:.||||
Human   277 VGNVTAALKSSGLWNNTVFIFSTDNGGQTLA----GGNNWPLRGRKWSLWEGGVRGVGFVASPLL 337

  Fly   328 KERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPR-TMIHVLDEVFGY 391
            |::|..:.:.||..||||||...|........||||.::|..:| ...|.|| .::|.:|..|..
Human   338 KQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTIS-EGSPSPRIELLHNIDPNFVD 401

  Fly   392 SS-YMRDTLKYVNGSSFKGRYDQWLGELETNEDDPLGESYEQHVLASDVQSLLGNRGLTKDRIRQ 455
            || ..|:::......|....|..:            ..|....:...:.:.|.|..|
Human   402 SSPCPRNSMAPAKDDSSLPEYSAF------------NTSVHAAIRHGNWKLLTGYPG-------- 446

  Fly   456 MRSEATETC----PPIEGQNPLESHFKCEPLKAPCFFDLAKDPCERYNLAQMYPLQLQQLADELE 516
                    |    ||....|..|......|.|....||:.:||.||::|::.||..:.:|...|:
Human   447 --------CGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQ 503

  Fly   517 QIRKTAIPSARVPHSDSRANPTFHNGNWEWW 547
            ...|.::| ...|..|.|.:|. ..|.|..|
Human   504 FYHKHSVP-VYFPAQDPRCDPK-ATGVWGPW 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	4-S	28..436	CDD:293753	166/412 (40%)
ARSB	NP_000037.2	4-S	45..488	CDD:293753	182/481 (38%)