Protein Alignment CG7402 and ARSA

DIOPT Version :10

• Sequence 1: NP_649023.1
• Gene: CG7402 / 39994
• FlyBaseID: FBgn0036768
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_000478.3
• Gene: ARSA / 410
• HGNCID: 713
• Length: 509
• Species: Homo sapiens
• Alignment Length: 560
• Identity: 156/560 - (27%)
• Similarity: 227/560 - (40%)
• Gaps: 142/560 - (25%)

  Fly    13 SSILSLAYGSGYSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVP-NLCT 76
            |.:|:||.|...:..||||:|..||:|..|:..:|.....|||:|.||..|:.....||| :|||
Human     8 SLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCT 72

  Fly    77 PSRATLLTGKYPIHTGMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKD-LT 140
            ||||.||||:.|:..||...|::.....|||..|..:.|:....||.|.:.||||||...:. ..
Human    73 PSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFL 137

  Fly   141 PTMRGFDHHFGYYNGYIDYYDHQVRMLDRNYSAGLDFRRDLEPC------PEAN----------- 188
            |..:|| |.|                      .|:.:..|..||      |.|.
Human   138 PPHQGF-HRF----------------------LGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLV 179

  Fly   189 -----GTYATEAFTS-----EAKRIIEQHD-------KSKPLFM-VLSHLAVHTGNEDSPMQAPE 235
                 ...:.||...     ||:.:...||       :.:|.|: ..||   ||.......|:..
Human   180 PIPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASH---HTHYPQFSGQSFA 241

  Fly   236 EEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGS 300
            |...:.|         :...:..||.:|...:.|:.|.|:|..::::..:|||..|:.: |..|.
Human   242 ERSGRGP---------FGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRM-SRGGC 296

  Fly   301 NYPYRGQKESPWEGGIRS-AGALWSPLLKERGYVSNQAIH----AVDWLPTLAGAAGVSLPQDLP 360
            :...|..|.:.:|||:|. |.|.|.      |:::....|    ::|.|||||..||..|| ::.
Human   297 SGLLRCGKGTTYEGGVREPALAFWP------GHIAPGVTHELASSLDLLPTLAALAGAPLP-NVT 354

  Fly   361 LDGINLWPMLSGNEEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQWLGELETNEDDP 425
            |||.:|.|:|.|..: .||      ..:|.|.||..:.         :|.:....|:
Human   355 LDGFDLSPLLLGTGK-SPR------QSLFFYPSYPDEV---------RGVFAVRTGK-------- 395

  Fly   426 LGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEATETCPPIEGQNPLESHFKCEPLKAPCFFDL 490
                |:.|.....                ...|:.|.. |.....:.|.:|   ||   |..:||
Human   396 ----YKAHFFTQG----------------SAHSDTTAD-PACHASSSLTAH---EP---PLLYDL 433

  Fly   491 AKDPCERYNL----AQMYPLQLQQLADELEQIRKTAIPSA 526
            :|||.|.|||    |...|..||.|  :..|:.|..:.:|
Human   434 SKDPGENYNLLGGVAGATPEVLQAL--KQLQLLKAQLDAA 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	4-S	28..436	CDD:293753	126/449 (28%)
ARSA	NP_000478.3	ARSA	22..505	CDD:293777	151/546 (28%)