DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7402 and Ids

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_647814.1	Gene:	Ids / 38423	FlyBaseID:	FBgn0035445	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	563	Identity:	114/563 - (20%)
Similarity:	190/563 - (33%)	Gaps:	206/563 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTSGKILVLLVVSSILSLAYGSGYSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGIL 65
            |.:.::|:.|::..:|..|   ....:||:|:::.||: ...:..:|.....||.:|..|....:
  Fly     1 MITARLLLSLMMPVLLDAA---APPRRPNVVMVIFDDL-RPVIGAYGDTLASTPYLDNFARGSHI 61

  Fly    66 LNKHY-VPNLCTPSRATLLTGKYP--IH-----------TGMQHFVIITDEPWGLPQRERLMPEI 116
            ..:.| ..:||.|||.:||||:.|  :|           ||  :|.              .:|:.
  Fly    62 FTRVYSQQSLCAPSRNSLLTGRRPDTLHLYDFYSYWRTFTG--NFT--------------TLPQY 110

  Fly   117 FRDAGYSTHLVGK-WHLGFWRKDLTPTMRGFDHHFGYYNGYIDYYDHQVRMLDRNYSAGLDFRRD 180
            |::.||.|:..|| :|.|.                 ..|...||        ..::||.. ||..
  Fly   111 FKEHGYYTYSCGKVFHPGL-----------------SSNNTDDY--------PLSWSAPA-FRPR 149

  Fly   181 LEP------CPEANG----------TYATEAF--------TSEAKRIIEQHDK--SKPLFMVLSH 219
            .|.      ||:..|          ...|:.:        .:||.|.:....:  .:|.|:.:..
  Fly   150 TEQFMNSPVCPDKEGILRKNLICPVELQTQPYKTLPDIESVAEALRFVGSRSRHSQEPFFLAMGF 214

  Fly   220 LAVHTG-------------------NEDS--PMQAPEEEVAKFPHIR---DPK------------ 248
            ...|..                   .|||  |...|......:..:|   |.|
  Fly   215 HKPHINFRFPRQFLSRFNLSQFYNYTEDSLKPPDMPAVAWNPYTDVRARDDFKHSNISFPYGPIS 279

  Fly   249 -------RRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYRG 306
                   |::|...:|.:|....:.||.|.    |:.::::...|:|. ::|.|:        ..
  Fly   280 PLQAAQIRQSYYASVSYVDDLFGKLIGGLD----LDETVVVALGDHGW-SLGEHA--------EW 331

  Fly   307 QKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAV----DWLPTLAGAAGVSLP--------QDL 359
            .|.|.:|..:|....:.||   :......:..|.:    |..|||...||  ||        |:|
  Fly   332 AKYSNFEVALRVPLIIRSP---QFPVAQTKYYHGITELLDVFPTLVDLAG--LPKLDKCQSSQEL 391

  Fly   360 PL-DGINLWPMLSG-------------------------NEEPKPRTMIHVLDEVFGYSSYMRDT 398
            .. :|.:|:..|.|                         :::||.|.:     ::.|||  :|..
  Fly   392 TCGEGKSLYHQLMGLGRADEHVALSQYPRPGMLPTKHPNSDKPKLRNI-----KIMGYS--LRTD 449

  Fly   399 LKYVNGSSFKGRYDQWL----GELETNEDDPLGESYEQHVLAS 437
            :.         ||..|:    .....:..|..||....|.|.|
  Fly   450 IY---------RYTMWVRFHAQNFSRDWHDVYGEELYDHRLDS 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	109/539 (20%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	107/533 (20%)
Ids	NP_647814.1	AslA	21..509	CDD:225661	109/540 (20%)
Ids	NP_647814.1	iduronate-2-sulfatase	24..495	CDD:293754	109/537 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466505
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740