DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7402 and CG18278

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_725289.1	Gene:	CG18278 / 36487	FlyBaseID:	FBgn0033836	Length:	492	Species:	Drosophila melanogaster

Alignment Length:	558	Identity:	133/558 - (23%)
Similarity:	209/558 - (37%)	Gaps:	135/558 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LVLLVVSSILSLAYGSGYSTK-PNIVIILIDDMGMNDVSFHGSNQILTP---NIDALAYNGILLN 67
            |::||::.:     |:..|.| |||::||.||   .||...|    :.|   .|:.|.:.|.|.:
  Fly     7 LIILVLACL-----GNTASEKLPNILLILSDD---QDVELRG----MFPMEHTIEMLGFGGALFH 59

  Fly    68 KHYVPN-LCTPSRATLLTGKYPIHTGMQHFVI---ITDEPWGLPQRERLMPEIFRDAGYSTHLVG 128
            ..|.|: :|.|:|.:||||.|..:.|.::..:   .....|......|.:|.|.:..||:|...|
  Fly    60 NAYTPSPICCPARTSLLTGMYAHNHGTRNNSVSGGCYGPHWRRALEPRALPYILQQHGYNTFFGG 124

  Fly   129 KWHLGFWRKDLTPTMRGFDHHFGYYNGYIDYYDHQVRMLDRNYSAGLDFRRDLEPCPEANGTYAT 193
            |:...:|.....|  :|::|.:|.: |...||::.:|....|.              ....||.|
  Fly   125 KYLNQYWGAGDVP--KGWNHFYGLH-GNSRYYNYTLRENSGNV--------------HYESTYLT 172

  Fly   194 EAFTSEAKRIIEQ-HDKSKPLFMVLSHLAVHTGNEDSPM-QAPEEEVAKFPHI---RDPK----- 248
            :.....|...:.. ...|:|.|.:::..|.|     .|. .||..| ..|.||   |.|.
  Fly   173 DLLRDRAADFLRNATQSSEPFFAMVAPPAAH-----EPFTPAPRHE-GVFSHIEALRTPSFNQVK 231

  Fly   249 ----------RR----------TYA----GMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGA 289
                      ||          ||.    ..:.::|:.|...:|.|.|...|.|:.|:..|||
  Fly   232 QDKHWLVRAARRLPNETINTIDTYFQKRWETLLAVDELVVTLMGVLNDTQSLENTYIIYTSDN-- 294

  Fly   290 PTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVS 354
               |.|....:. |:  .|..|:|..|.....:..|.:....:: :.|:..||..||:...|.:.
  Fly   295 ---GYHVGQFAQ-PF--DKRQPYETDINVPLLIRGPGIAPESHI-DTAVSLVDLAPTILAWADID 352

  Fly   355 LPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGS---SFKGRYDQWLG 416
            .|.  .:||.:...:|.......|.....:|.|.:|     ..||...|..   ..|.|..|...
  Fly   353 TPS--YMDGQSFHELLLNKRRRVPFFERSLLIEYWG-----EGTLATFNPECPWPEKDRLAQCTP 410

  Fly   417 ELETNEDDPLGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEATETCPPIEGQNPLESHFKCEP 481
            ..:.:..|....:|          :.|.|....:|||         .|...:.:|.||:
  Fly   411 AADCHCQDAWNNTY----------ACLRNIRHREDRI---------YCEFRDNENFLEA------ 450

  Fly   482 LKAPCFFDLAKDPCERYNLA--------QMYPLQLQQL 511
                  :||..||.:..|:|        .:|.|:|:.|
  Fly   451 ------YDLQLDPFQMTNIAYDLLPIERALYSLRLKNL 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	115/478 (24%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	108/451 (24%)
CG18278	NP_725289.1	G6S	24..467	CDD:293766	123/519 (24%)
CG18278	NP_725289.1	AslA	24..464	CDD:225661	122/516 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740