Protein Alignment CG7402 and ARSH

DIOPT Version :9

• Sequence 1: NP_649023.1
• Gene: CG7402 / 39994
• FlyBaseID: FBgn0036768
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001011719.1
• Gene: ARSH / 347527
• HGNCID: 32488
• Length: 562
• Species: Homo sapiens
• Alignment Length: 624
• Identity: 154/624 - (24%)
• Similarity: 230/624 - (36%)
• Gaps: 170/624 - (27%)

  Fly    25 STKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHY-VPNLCTPSRATLLTGKYP 88
            :.:||||:::.||:|:.|:..:|:|.:.|||||.||..|:.|.:|. ..::||||||..|||:||
Human     4 NARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGRYP 68

  Fly    89 IHTGM-QHFVIITDEPW-----GLPQRERLMPEIFRDAGYSTHLVGKWHLGF---WRKD--LTPT 142
            |.:|| ..:.:.....|     |||..|....::.:..||.|.|:||||||.   .|.|  ..|.
Human    69 IRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRNDHCYHPL 133

  Fly   143 MRGFDHHFG-------------------------------------------------------- 151
            ..||.:.:|
Human   134 NHGFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFLLLIPKFARWFSVPWKVIF 198

  Fly   152 --------YYNGYIDYYDHQVR---MLDRNYSAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIE 205
                    ::..:...|....|   :|.||:..      ..:|..|..   .......||...||
Human   199 VFALLAFLFFTSWYSSYGFTRRWNCILMRNHEI------IQQPMKEEK---VASLMLKEALAFIE 254

  Fly   206 QHDKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGAL 270
            :: |.:|..:..|.|.|||     |:      ::|...:...|...|...:..:|..|.:.:.||
Human   255 RY-KREPFLLFFSFLHVHT-----PL------ISKKKFVGRSKYGRYGDNVEEMDWMVGKILDAL 307

  Fly   271 KDNGMLNNSIILLYSDNGA---PTIGIHSNAGSNYPYRGQK-ESPWEGGIRSAGALWSPLLKERG 331
            ....:.|::::...||||.   |..|.....|.|..|:|.| ...||||||..|....|.:.|.|
Human   308 DQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPSVLEAG 372

  Fly   332 YVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFGYSSYMR 396
            .|.|:....:|..|||:...|..|.||..:||.||.|:|.|.........:      |.|.....
Human   373 RVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFL------FHYCGVYL 431

  Fly   397 DTLKYVNGSSFKGRYDQWLGELETNEDDP--LGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSE 459
            .|:::..    |.....|.....|.:..|  .|..|     .|.:.|..|              :
Human   432 HTVRWHQ----KDCATVWKAHYVTPKFYPEGTGACY-----GSGICSCSG--------------D 473

  Fly   460 ATETCPPIEGQNPLESHFKCEPLKAPCFFDLAKDPCERYNL----AQMYPLQLQQLADELEQIRK 520
            .|...||:                   .||:::||.|...|    ..::...::::...:.:.|:
Human   474 VTYHDPPL-------------------LFDISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRR 519

  Fly   521 TAIPSARVPHSDSRANPTFHNGNWEWWNNTDTQSGSGTF 559
            |..|   ||...|     ..|..|:.|    .|...|||
Human   520 TLTP---VPQQFS-----VFNTIWKPW----LQPCCGTF 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	132/518 (25%)
		4-S	28..436	CDD:293753	129/492 (26%)
ARSH	NP_001011719.1	ALP_like	6..530	CDD:304875	147/600 (25%)
		AslA	6..437	CDD:225661	123/457 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157177
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740