DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7402 and Sulf2

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001030099.1	Gene:	Sulf2 / 311642	RGDID:	1305078	Length:	875	Species:	Rattus norvegicus

Alignment Length:	559	Identity:	111/559 - (19%)
Similarity:	202/559 - (36%)	Gaps:	166/559 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVVSSILSLAYGSG----------------YSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDA 58
            |:.:::.||..||.                .:.:|||:::|.||   .||.. ||.|::......
  Rat    10 LLSTALFSLLAGSSAFLSYPRLKGRFQRDRRNIRPNIILVLTDD---QDVEL-GSMQVMNKTRRI 70

  Fly    59 LAYNGI-LLNKHYVPNLCTPSRATLLTGKYPIHTGMQHFVIITDE-----PWGLPQRERLMPEIF 117
            :...|. .:|......:|.|||:::||||| :|   .|.....:|     .|......|......
  Rat    71 MEQGGAHFINAFVTTPMCCPSRSSILTGKY-VH---NHNTYTNNENCSSPSWQAQHESRTFAVYL 131

  Fly   118 RDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHFGYYNG-YID--------------YYDHQVRML 167
            ...||.|...||                   :...||| |:.              :|::.:...
  Rat   132 NSTGYRTAFFGK-------------------YLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRN 177

  Fly   168 DRNYSAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIEQHDK---SKPLFMVLSHLAVHTGNEDS 229
            ......|.|:..|          |.|:..|:::........|   .:|:.||:||.|.| |.|||
  Rat   178 GMKEKHGSDYSTD----------YLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPH-GPEDS 231

  Fly   230 PMQ------------------APEEE---VAKFPHIRDPKRRTYAGMIS--------SLDKSVAQ 265
            ..|                  ||..:   :.::.....|....:..|:.        |:|.|:..
  Rat   232 APQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMET 296

  Fly   266 TIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYRGQ------KESPWEGGIRSAGALWS 324
            ....|.:.|.|:|:.|:..:|:|.              :.||      |..|:|..||....:..
  Rat   297 IYDMLVETGELDNTYIVYTADHGY--------------HIGQFGLVKGKSMPYEFDIRVPFYVRG 347

  Fly   325 PLLKERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVF 389
            |.: |.|.::...:..:|..||:...||:.:|.|  :||.::..:|   :..:|....|:..::.
  Rat   348 PSV-EAGSLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLL---DSERPVNRFHLKKKLR 406

  Fly   390 GY-SSYMRDTLKYVN---GSSFKGRYDQWLGELETNED-----------DPLGESYEQHVLASDV 439
            .: .|::.:..|.::   |.....:.:.:|.:.:..:|           :.||:.::   ...|.
  Rat   407 VWRDSFLVERGKLLHKREGDKVNAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQ---CVEDA 468

  Fly   440 QSLL--------------GNRGLTKDRIRQMRSEATETC 464
            ...|              |:|.|: :.:.:...:::|.|
  Rat   469 SGALKLHKCKGPVRFGGGGDRALS-NLVPKYDGQSSEAC 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	104/521 (20%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	99/481 (21%)
Sulf2	NP_001030099.1	G6S	43..385	CDD:293766	89/396 (22%)
		DUF3740	533..666	CDD:403667
		ALP_like	<754..803	CDD:419962
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351089
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740