DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7402 and Galns

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_017456734.1	Gene:	Galns / 292073	RGDID:	1565391	Length:	567	Species:	Rattus norvegicus

Alignment Length:	481	Identity:	136/481 - (28%)
Similarity:	204/481 - (42%)	Gaps:	98/481 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 PNLCTP----SRATLLTGKYPIHTGM-------QHFVIITDEPWGLPQRERLMPEIFRDAGYSTH 125
            |..|..    |||.||||:.||..|.       ::.....:...|:|..|.|:||:.:.|||:..
  Rat   116 PQHCATAHGRSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIMGGIPNSEHLLPELLKKAGYTNK 180

  Fly   126 LVGKWHLGFWRKDLTPTMRGFDHHFGYYNGYIDYYDHQVR----------MLDRNYSAGLDFRRD 180
            :|||||||. |....|...|||..||..|.:...||::|:          |:.|.|.   :|..:
  Rat   181 IVGKWHLGH-RPQFHPLKHGFDEWFGSPNCHFGPYDNKVKPNIPVYRDWEMVGRFYE---EFPIN 241

  Fly   181 LEPCPEANGTYATEAFTSEAKRIIE-QHDKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHI 244
            |: ..|||   .|:.:..||...|. ||.:..|.|:..:..|.|     :|:.|.::      .:
  Rat   242 LK-TGEAN---LTQLYLQEALDFIRTQHARQSPFFLYWAIDATH-----APVYASKQ------FL 291

  Fly   245 RDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYRGQKE 309
            ....|..|...:..:|.||.:.:..|::.|:..|:.:...|||||..|......|||.|:...|:
  Rat   292 GTSLRGRYGDAVREIDDSVGKILSLLQNLGISKNTFVFFTSDNGAALISAPKEGGSNGPFLCGKQ 356

  Fly   310 SPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWP-MLSGN 373
            :.:|||:|.....|.|.....|.||:|....:|...|....||:..|.|..:||::|.| ||.|
  Rat   357 TTFEGGMREPAIAWWPGHIAAGQVSHQLGSIMDLFTTSLSLAGLKPPSDRVIDGLDLLPTMLQG- 420

  Fly   374 EEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQWLGELETNEDDPLGESYEQHVLASD 438
                     |::|....|  |..:||..|....:|.....|     ||       |:|:
  Rat   421 ---------HIIDRPIFY--YRGNTLMAVTLGQYKAHLWTW-----TN-------SWEE------ 456

  Fly   439 VQSLLGNRGLTKDRIRQMRSEATETCPPIEGQN--PLESHFKCEPLKAPCFFDLAKDPCERYNL- 500
                          .||    ..:.||   |||  .:.:|.:.|..:.|..|.|.:||.||:.|
  Rat   457 --------------FRQ----GIDFCP---GQNVSGVTTHTQEEHTELPLIFHLGRDPGERFPLR 500

  Fly   501 --AQMYPLQLQQLADELEQIRKTAIP 524
              :..|...|.:....::|.:|:.:|
  Rat   501 FTSNEYQDALSRTTQVIQQHQKSLVP 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	116/409 (28%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	114/386 (30%)
Galns	XP_017456734.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351139
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740