Protein Alignment CG7402 and GALNS

DIOPT Version :10

• Sequence 1: NP_649023.1
• Gene: CG7402 / 39994
• FlyBaseID: FBgn0036768
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_011521284.1
• Gene: GALNS / 2588
• HGNCID: 4122
• Length: 581
• Species: Homo sapiens
• Alignment Length: 543
• Identity: 152/543 - (27%)
• Similarity: 226/543 - (41%)
• Gaps: 126/543 - (23%)

  Fly    37 DMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPN-LCTPSRATLLTGKYPIHTGM------- 93
            :||..|:..:|.....|||:|.:|..|:|....|..| ||:||||.||||:.||..|.
Human    46 EMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCSPSRAALLTGRLPIRNGFYTTNAHA 110

  Fly    94 ------QHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHFGY 152
                  |..|      .|:|..|:|:||:.:.|||.:.:|||||||. |....|...|||..||.
Human   111 RNAYTPQEIV------GGIPDSEQLLPELLKKAGYVSKIVGKWHLGH-RPQFHPLKHGFDEWFGS 168

  Fly   153 YNGYIDYYDHQVR----------MLDRNYSAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIEQH 207
            .|.:...||::.|          |:.|.|.   :|..:|: ..|||   .|:.:..||...|::.
Human   169 PNCHFGPYDNKARPNIPVYRDWEMVGRYYE---EFPINLK-TGEAN---LTQIYLQEALDFIKRQ 226

  Fly   208 DKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKD 272
            .:..|.|:..:..|.|     :|:.|.:      |.:...:|..|...:..:|.|:.:.:..|:|
Human   227 ARHHPFFLYWAVDATH-----APVYASK------PFLGTSQRGRYGDAVREIDDSIGKILELLQD 280

  Fly   273 NGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGYVSNQA 337
            ..:.:|:.:...|||||..|......|||.|:...|::.:|||:|.....|.|.....|.||:|.
Human   281 LHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQL 345

  Fly   338 IHAVDWLPTLAGAAGVSLPQDLPLDGINLWP-MLSGNEEPKPRTMIHVLDEVFGYSSYMRDTLKY 401
            ...:|...|....||::.|.|..:||:||.| :|.|          .::|....|  |..|||..
Human   346 GSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQG----------RLMDRPIFY--YRGDTLMA 398

  Fly   402 VNGSSFKGRYDQWLGELETNEDDPLGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEATETCPP 466
            ......|..:..|     ||.    .|::.|.:                           :.||
Human   399 ATLGQHKAHFWTW-----TNS----WENFRQGI---------------------------DFCP- 426

  Fly   467 IEGQN-------PLESHFKCEPLKAPCFFDLAKDPCERYNL---AQMYPLQLQQLADELEQIRKT 521
              |||       .||.|     .|.|..|.|.:||.||:.|   :..|...|.::...::|.::.
Human   427 --GQNVSGVTTHNLEDH-----TKLPLIFHLGRDPGERFPLSFASAEYQEALSRITSVVQQHQEA 484

  Fly   522 AIPSARVPHSDSRANPTFHNGNW 544
            .:|          |.|..:..||
Human   485 LVP----------AQPQLNVCNW 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	4-S	28..436	CDD:293753	127/423 (30%)
GALNS	XP_011521284.1	GALNS	46..500	CDD:293776	152/543 (28%)