DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7402 and Sulf1

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_006495573.1	Gene:	Sulf1 / 240725	MGIID:	2138563	Length:	1121	Species:	Mus musculus

Alignment Length:	571	Identity:	125/571 - (21%)
Similarity:	210/571 - (36%)	Gaps:	153/571 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPN-LCTPSRATLLTGKYPIH 90
            :|||:::|.||   .||.. ||.|::......:...|......:|.. :|.|||:::||||| :|
Mouse    42 RPNIILVLTDD---QDVEL-GSLQVMNKTRKIMEQGGATFTNAFVTTPMCCPSRSSMLTGKY-VH 101

  Fly    91 TGMQHFVIITDE-----PWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHF 150
               .|.|...:|     .|......|.......:.||.|...||                   :.
Mouse   102 ---NHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGK-------------------YL 144

  Fly   151 GYYNG-YID--------------YYDHQVRMLDRNYSAGLDFRRDLEPCPEANGTYATEAFTSEA 200
            ..||| ||.              :|::.|.........|.|:.:|          |.|:..|:|:
Mouse   145 NEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKD----------YFTDLITNES 199

  Fly   201 KRIIEQHDK---SKPLFMVLSHLAVHTGNEDSPMQ------------------APEEEV------ 238
            ....:...:   .:|:.||:||.|.| |.|||..|                  ||..:.
Mouse   200 INYFKMSKRMYPHRPIMMVISHAAPH-GPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQY 263

  Fly   239 --------AKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIH 295
                    .:|.::...||   ...:.|:|.||.:....|.::|.|:|:.|:..:|:|
Mouse   264 TGPMLPIHMEFTNVLQRKR---LQTLMSVDDSVERLYNMLVESGELDNTYIIYTADHG------- 318

  Fly   296 SNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLP 360
            .:.|.....:| |..|::..||....:..|.: |.|.:..|.:..:|..||:...||:..|.|
Mouse   319 YHIGQFGLVKG-KSMPYDFDIRVPFFIRGPSI-EPGSIVPQIVLNIDLAPTILDIAGLDSPSD-- 379

  Fly   361 LDGINLWPMLSGNEEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQWLGELETNEDDP 425
            :||.::..:|. .|:|..|...:...:::      |||.....|...:.:.:.
Mouse   380 VDGKSVLKLLD-LEKPGNRFRTNKKAKIW------RDTFLVERGKFLRKKEES------------ 425

  Fly   426 LGESYEQHVLASDVQSLLGNRGLTK-DRIRQMRSEAT-ETCPPIEGQNPLESHFKC-EPLKAPCF 487
             |::.:|            :..|.| :|::::..:|. :|.....|||     ::| |.......
Mouse   426 -GKNIQQ------------SNHLPKYERVKELCQQARYQTACEQPGQN-----WQCIEDTSGKLR 472

  Fly   488 FDLAKDPCE----RYNLAQMYPLQLQQLADELEQIRKTAIPSARVPHSDSR 534
            ....|.|.:    |.|...:|...|.. .|:....|.:...|:|....:.|
Mouse   473 IHKCKGPSDLLTVRQNARNLYSRGLHD-KDKECHCRDSGYRSSRSQRKNQR 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	107/488 (22%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	104/463 (22%)
Sulf1	XP_006495573.1	G6S	42..384	CDD:293766	94/393 (24%)
		DUF3740	534..674	CDD:403667
		ALP_like	<767..816	CDD:419962
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847543
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740