DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7402 and sul-3

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001360719.1	Gene:	sul-3 / 183778	WormBaseID:	WBGene00006310	Length:	484	Species:	Caenorhabditis elegans

Alignment Length:	554	Identity:	163/554 - (29%)
Similarity:	261/554 - (47%)	Gaps:	97/554 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LVLLVVSSILSLAYGSGYSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAY--NGILLNKH 69
            |:||:.:..::...|...:.|||::.|:.||:|.:||.:..|. :.|||:..||:  |..||:..
Worm    10 LLLLLHNHGITGVDGQTATQKPNVLFIMADDLGFSDVDWKDST-LHTPNLRHLAFHKNTALLSNS 73

  Fly    70 YVPNLCTPSRATLLTGKYPIHTGMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGF 134
            ||..||||:|:..:||.||...|.|:.|.:..||.|:|.....:.|..|...|||:||||||||:
Worm    74 YVNQLCTPTRSAFMTGYYPFRVGTQNGVFLHMEPAGVPTMFPFLSENMRQLDYSTYLVGKWHLGY 138

  Fly   135 WRKDLTPTMRGFDHHFGYYNGYIDYYDHQVRMLDRNYS---AGLDFRRDL---EPCPE--ANGTY 191
            .:|:..||.||||:.:|:|.....|::|......|...   .|||...::   :..|:  .||.|
Worm   139 CKKEFLPTNRGFDYFYGFYGPQTGYFNHSADQYHRELKRVVKGLDLFEEVGSGKSVPDFSQNGVY 203

  Fly   192 ATEAFTSEAKRIIEQHDKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMI 256
            :|:.||..|..:::.|:.|||.||.||:.|||     .|:|.|.........:::..||.|.||:
Worm   204 STDLFTDVAMSVLDNHNNSKPFFMFLSYQAVH-----PPLQVPRSFDKYCTRVKNRYRRIYCGML 263

  Fly   257 SSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYRGQKESPWEGGIRSAGA 321
            :::|.::.:.:..||.:.:..|::|:..||||    |..:...||.|.||:|::.||||.::...
Worm   264 TAMDFAIGRLVEYLKASNLYENTVIVFTSDNG----GTANFGASNAPLRGEKDTIWEGGTKTTTF 324

  Fly   322 LWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLD 386
            :.||:..|.|...:...|.|||..|:....|:.:  |...||||.|..|. ...||.|....|.:
Worm   325 VHSPMYIEEGGTRDMMFHVVDWHATILSITGLEI--DSYGDGINQWEYLK-TGRPKFRRFQFVYN 386

  Fly   387 EVFGYSSYMRDTLKYVNGSSFKGRYDQWLGELETNEDDPLGESYEQHVLASDVQSLLGN--RGLT 449
             :..:.|.:||                                       .|.:.::||  |.::
Worm   387 -IDNHGSAIRD---------------------------------------GDYKLIVGNVDRKMS 411

  Fly   450 KDRIRQMRSEATETCPPIEGQNPLESHFKCEPLKAPCFFDLAKDPCERYNLAQMYPLQLQQLADE 514
            ||:.|..                              .|.:..||.|..::|:..|..:::|..:
Worm   412 KDKNRTR------------------------------LFRITTDPTESKDIARSNPKIVRRLLAK 446

  Fly   515 LEQIRKTAIPSARVPHSDSRANPTFHNGNW-EWW 547
            |:|::|....:.|.|.| ...:|...||:: .:|
Worm   447 LDQLKKFLHKNVRKPLS-LNGSPERFNGSYSSYW 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	142/445 (32%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	134/417 (32%)
sul-3	NP_001360719.1	4-S	31..433	CDD:293753	145/484 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165362
Domainoid	1	1.000	224	1.000	Domainoid score	I1449
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	269	1.000	Inparanoid score	I1835
Isobase	1	0.950	-	0	Normalized mean entropy	S4796
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	1	1.000	-	-		FOG0000852
OrthoInspector	1	1.000	-	-		otm14696
orthoMCL	1	0.900	-	-		OOG6_100690
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X499
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.750