DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7402 and Sulf1

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_008761708.1	Gene:	Sulf1 / 171396	RGDID:	708554	Length:	1117	Species:	Rattus norvegicus

Alignment Length:	552	Identity:	122/552 - (22%)
Similarity:	202/552 - (36%)	Gaps:	164/552 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPN-LCTPSRATLLTGKYPIH 90
            :|||:::|.||   .||.. ||.|::......:.:.|......:|.. :|.|||:::||||| :|
  Rat    42 RPNIILVLTDD---QDVEL-GSLQVMNKTRKIMEHGGATFTNAFVTTPMCCPSRSSMLTGKY-VH 101

  Fly    91 TGMQHFVIITDEPWGLPQRERL-MPEIF----RDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHF 150
               .|.|...:|....|..:.| .|..|    .:.||.|...||                   :.
  Rat   102 ---NHNVYTNNENCSSPSWQALHEPRTFAVYLNNTGYRTAFFGK-------------------YL 144

  Fly   151 GYYNG-YID--------------YYDHQVRMLDRNYSAGLDFRRDLEPCPEANGTYATEAFTSEA 200
            ..||| ||.              :|::.|.........|.|:.:|          |.|:..|:|:
  Rat   145 NEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKD----------YFTDLITNES 199

  Fly   201 KRIIEQHDK---SKPLFMVLSHLAVHTGNEDSPMQ------------------APEEEV------ 238
            ....:...:   .:|:.||:||.|.| |.|||..|                  ||..:.
  Rat   200 INYFKMSKRMYPHRPVMMVISHAAPH-GPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQY 263

  Fly   239 --------AKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIH 295
                    .:|.::...||   ...:.|:|.||.:....|.:.|.|.|:.|:..:|:|.
  Rat   264 TGPMLPIHMEFTNVLQRKR---LQTLMSVDDSVERLYNMLVETGELGNTYIIYTADHGY------ 319

  Fly   296 SNAGSNYPYRGQ------KESPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVS 354
                    :.||      |..|::..||....:..|.: |.|.:..|.:..:|..||:...||:.
  Rat   320 --------HIGQFGLVKGKSMPYDFDIRVPFFIRGPSI-EPGSIVPQIVLNIDLAPTILDIAGLD 375

  Fly   355 LPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQWLGELE 419
            .|.|  :||.::..:|. .|:|..|...:...:::      |||.....|...:.:.:.
  Rat   376 TPSD--VDGKSVLKLLD-LEKPGNRFRTNKKAKIW------RDTFLVERGKFLRKKEES------ 425

  Fly   420 TNEDDPLGESYEQHVLASDVQSLLGNRGLTK-DRIRQMRSEAT-ETCPPIEGQNPLESHFKC-EP 481
                            :.::|.   :..|.| :|::::..:|. :|.....|||     ::| |.
  Rat   426 ----------------SKNIQQ---SNHLPKYERVKELCQQARYQTACEQPGQN-----WQCIED 466

  Fly   482 LKAPCFFDLAKDPCE----RYNLAQMYPLQLQ 509
            ..........|.|.:    |.|...:|...||
  Rat   467 TSGKLRIHKCKGPSDLLTVRQNARNLYSRGLQ 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	108/494 (22%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	104/469 (22%)
Sulf1	XP_008761708.1	G6S	42..384	CDD:293766	96/399 (24%)
		DUF3740	534..675	CDD:403667
		ALP_like	<767..816	CDD:419962
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351095
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740