DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7402 and Arsa

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_033843.2	Gene:	Arsa / 11883	MGIID:	88077	Length:	506	Species:	Mus musculus

Alignment Length:	545	Identity:	140/545 - (25%)
Similarity:	220/545 - (40%)	Gaps:	146/545 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LSLAYGSGYSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVP-NLCTPSR 79
            |:||.|...::.|||::|..||:|..|:..:|.....|||:|.||..|:.....||| :||||||
Mouse     8 LALAAGLSTASPPNILLIFADDLGYGDLGSYGHPSSTTPNLDQLAEGGLRFTDFYVPVSLCTPSR 72

  Fly    80 ATLLTGKYPIHTGMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKD-LTPTM 143
            |.||||:.|:.:||...|:......|||..|..:.|:....||.|.:.||||||...:. ..|..
Mouse    73 AALLTGRLPVRSGMYPGVLGPSSQGGLPLEEVTLAEVLAARGYLTGMAGKWHLGVGPEGAFLPPH 137

  Fly   144 RGFDHHFGYYNGYIDYYDHQVRMLDRNYSAGLDFRRDLEPC-------PE--------------- 186
            :|| |.|                      .|:.:..|..||       |:
Mouse   138 QGF-HRF----------------------LGIPYSHDQGPCQNLTCFPPDIPCKGGCDQGLVPIP 179

  Fly   187 --ANGTYATE---------AFTSEAKRII-EQHDKSKPLFM-VLSHLAVHTGNEDSPMQAPEEEV 238
              ||.|...:         .:.|.::.:: :...:.:|.|: ..||   ||.......|:..:..
Mouse   180 LLANLTVEAQPPWLPGLEARYVSFSRDLMADAQRQGRPFFLYYASH---HTHYPQFSGQSFTKRS 241

  Fly   239 AKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYP 303
            .:.|         :...:..||.:|...:..:.|.|:|..::::..:||| |.:...||.|.:..
Mouse   242 GRGP---------FGDSLMELDGAVGALMTTVGDLGLLEETLVIFTADNG-PELMRMSNGGCSGL 296

  Fly   304 YRGQKESPWEGGIRSAGALWSPLLKERGYVSNQAIH----AVDWLPTLAGAAGVSLPQDLPLDGI 364
            .|..|.:.:|||:|....::.|     |:::....|    ::|.|||||...|..|| ::.|||:
Mouse   297 LRCGKGTTFEGGVREPALVYWP-----GHITPGVTHELASSLDLLPTLAALTGAPLP-NVTLDGV 355

  Fly   365 NLWPMLSGNEEPKPRTMIHVL----DEVFGYSSYMRDTLKYVNGSSFKGRYDQWLGELETNEDDP 425
            ::.|:|.|..: .||..:...    ||:.|..:        |....:|..:
Mouse   356 DISPLLLGTGK-SPRKSVFFYPPYPDEIHGVFA--------VRNGKYKAHF-------------- 397

  Fly   426 LGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEATETCPPIEGQNPLESHFKCEPLKAPCFFDL 490
                :.|....||                      |.:.|.....|.|.:|   ||   |..:||
Mouse   398 ----FTQGSAHSD----------------------TTSDPACHAANRLTAH---EP---PLLYDL 430

  Fly   491 AKDPCERYNLAQ----MYPLQLQQL 511
            ::||.|.||:.:    :.|..||.|
Mouse   431 SQDPGENYNVLESIEGVSPEALQAL 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	117/478 (24%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	115/452 (25%)
Arsa	NP_033843.2	AslA	16..440	CDD:225661	131/520 (25%)
Arsa	NP_033843.2	ALP_like	19..502	CDD:304875	136/534 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847573
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740