DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7402 and arsj

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_002934299.2	Gene:	arsj / 100494972	XenbaseID:	XB-GENE-951842	Length:	564	Species:	Xenopus tropicalis

Alignment Length:	572	Identity:	199/572 - (34%)
Similarity:	290/572 - (50%)	Gaps:	82/572 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VLLVVSSILSLAYG-------------------------SGYSTKPNIVIILIDDMGMNDVSFHG 47
            ||...|::..:|||                         :|:  :|:||.||.||.|..|:.:||
Frog     4 VLTAFSALSLMAYGYLSWDSANSVLEDQKGSSEESPQRETGH--QPHIVFILADDQGYRDIGYHG 66

  Fly    48 SNQILTPNIDALAYNGILLNKHYVPNLCTPSRATLLTGKYPIHTGMQHFVIITDEPWGLPQRERL 112
            | :|.||.:|.||.:|:.|..:||..:|:|||:..:||||.||||:||.:|...:|..||.....
Frog    67 S-EIRTPTLDKLASDGVRLENYYVQPICSPSRSQFITGKYQIHTGLQHSIIRPSQPNCLPLDNMT 130

  Fly   113 MPEIFRDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHFGYYNGYIDYYDHQVRMLDRNYSAGLD- 176
            :|:..:.|||.||:||||||||::|:..||.||||..||...|..|||:|.  ..|.....|.|
Frog   131 LPQKLKKAGYQTHMVGKWHLGFYKKECMPTQRGFDSFFGSLLGSGDYYNHY--KCDSPGICGYDL 193

  Fly   177 FRRDLEPCPEANGTYATEAFTSEAKRIIEQHDKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKF 241
            :..:.....:.||.|:||.:|....:|:..|:.:||||:.:::.|||     ||:|||...:..:
Frog   194 YENNNAAWDQDNGIYSTEMYTQRVLQILSSHNPNKPLFLYIAYQAVH-----SPLQAPGNYLDNY 253

  Fly   242 PHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGA-PTIGIHSNAGSNYPYR 305
            ..|.:..||.||.|:|.||.:|.....|||..|..:||||:..||||. |..|     |:|:|.|
Frog   254 NSILNENRRRYAAMLSCLDDAVNNVTTALKKYGFYDNSIIIYSSDNGGQPMAG-----GNNWPLR 313

  Fly   306 GQKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPML 370
            |.|.:.||||||:.|.:.||:||.:||:..:.:|..||.|||...||..:.:::.|||.::|..:
Frog   314 GSKGTYWEGGIRAVGFVHSPILKMKGYICKELVHITDWFPTLVTLAGGEIDEEIQLDGYDIWETI 378

  Fly   371 SGNEEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQWLGELETNEDDPLGESYEQHVL 435
            |..:....:.::|.:|.::         .|..|||...| |..|            ..:.:..:.
Frog   379 SEGKRSPRQEILHNIDPMY---------TKARNGSWAAG-YGIW------------NTAIQSAIR 421

  Fly   436 ASDVQSLLGNRGLTKDRIRQMRSEATETCPPIEGQN--PLESHFKCEPL---KAPCFFDLAKDPC 495
            .:..:.|.||.|.            .:..||....|  |...|.:...|   |:...|::..||.
Frog   422 VNHWKLLTGNPGY------------GDWIPPQSFSNVGPNRWHNERVTLASGKSVWLFNITADPY 474

  Fly   496 ERYNLAQMYPLQLQQLADELEQIRKTAIPSARVPHSDSRANPTFHNGNWEWW 547
            ||.:|:..||..::||...|.|..|||:| .|.|..|.|:||..:.|.|..|
Frog   475 ERIDLSDRYPDIVKQLLRRLAQFNKTAVP-VRYPPRDPRSNPKLNGGVWGPW 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	160/435 (37%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	156/409 (38%)
arsj	XP_002934299.2	4-S	47..480	CDD:293753	172/479 (36%)
arsj	XP_002934299.2	DUF4976	<466..>504	CDD:419068	16/38 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	300	1.000	Domainoid score	I1405
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2217
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	1	1.000	-	-		FOG0000852
OrthoInspector	1	1.000	-	-		mtm9380
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X499
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970