DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7402 and arsb

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_002940244.3	Gene:	arsb / 100493013	XenbaseID:	XB-GENE-962085	Length:	520	Species:	Xenopus tropicalis

Alignment Length:	538	Identity:	198/538 - (36%)
Similarity:	285/538 - (52%)	Gaps:	61/538 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 STKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPNLCTPSRATLLTGKYPI 89
            ::.|:||.:|.||:|.|||.|||| :||||.:|.|:..|:.|..:|...||||||:.||:|:|.|
Frog    28 ASPPHIVFVLADDLGWNDVGFHGS-EILTPTLDFLSGQGVRLAGYYTQPLCTPSRSQLLSGRYQI 91

  Fly    90 HTGMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHFGYYN 154
            |||:||.:|...:|...|..::|:||:.::.||.||:|||||||.::.|..||.||||.:|||:.
Frog    92 HTGLQHQIIWPCQPHCHPLEDKLLPELLKERGYVTHMVGKWHLGMYKTDCLPTRRGFDSYFGYWT 156

  Fly   155 GYIDYYDHQVRMLDRNY--------SAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIEQHDKSK 211
            |..|||.|     :|.|        ...||||....|..:....|:|..||..|..:|..|:..|
Frog   157 GGEDYYSH-----ERCYLITTLNITRCALDFRDGEVPATDYQMKYSTHLFTDRAVDLITNHNPEK 216

  Fly   212 PLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGML 276
            |||:.|::.|||     ||:|.|::.:..:..|.|..||.||||:|.||::||....|||..|:.
Frog   217 PLFLYLAYQAVH-----SPLQVPDQYIEPYTSIHDKNRRLYAGMVSVLDEAVANVTNALKKQGLW 276

  Fly   277 NNSIILLYSDNGAPTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAV 341
            ||::.:..:|||..|:    :.|:|:|.||:|.:.||||||..|.:.|.|||::|..|.:.||..
Frog   277 NNTVFIFSTDNGGQTL----SGGNNWPLRGRKWTLWEGGIRGVGFVTSSLLKQKGVTSKELIHIS 337

  Fly   342 DWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPRT-MIHVLDEVF------GYSSYMRDTL 399
            ||||||...||.|.....||||.::|..:| ...|.||. ::|.:|.:|      ..|...||..
Frog   338 DWLPTLVNLAGGSTNSTKPLDGFDVWKTIS-EGSPSPRVELLHNIDPLFEDSFPCSVSPNTRDQA 401

  Fly   400 KYVNGSSFKGRYDQWLGELETNEDDPLGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEATETC 464
            .....:       :|       :|.|...|....:...:.:.|.||.|.:  ......|:.:| .
Frog   402 PTHAAT-------KW-------QDSPFNVSVHAAIRHGNWKLLTGNPGCS--HWFPPPSKHSE-I 449

  Fly   465 PPIEGQNPLESHFKCEPLKAPCFFDLAKDPCERYNLAQMYPLQLQQLADELEQIRKTAIPSARVP 529
            |..:|.|           |....||:.:||.|||:|::.:|..:..|...|:....:::| ...|
Frog   450 PSPDGSN-----------KTLWLFDIVQDPEERYDLSEKFPDVVTMLLFRLQNYYISSVP-IDYP 502

  Fly   530 HSDSRANPTFHNGNWEWW 547
            ..|.|.:|. ..|.|..|
Frog   503 DDDPRCDPG-DKGVWGPW 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	173/448 (39%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	169/422 (40%)
arsb	XP_002940244.3	4-S	31..475	CDD:293753	186/487 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H73870
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010