DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7402 and arsi

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_002940132.1	Gene:	arsi / 100487216	XenbaseID:	XB-GENE-6046190	Length:	575	Species:	Xenopus tropicalis

Alignment Length:	551	Identity:	182/551 - (33%)
Similarity:	278/551 - (50%)	Gaps:	61/551 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 STKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPNLCTPSRATLLTGKYPI 89
            |..|:|:.||.||.|.:||.:|||: |.||.:|.||..|:.|..:|:..:|||||:.|:||:|.|
Frog    46 SRPPHIIFILTDDQGFHDVGYHGSD-IQTPTLDRLAAEGVKLENYYIQPICTPSRSQLITGRYQI 109

  Fly    90 HTGMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHFGYYN 154
            |||:||.:|...:|..||..:..:|:..::||||||:||||||||::|:..||.||||...|...
Frog   110 HTGLQHSIIRPRQPNCLPLHQVTLPQKLQEAGYSTHMVGKWHLGFYKKECLPTRRGFDTFLGSLT 174

  Fly   155 GYIDYYDHQVRMLDRNYSAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIEQHDKSKPLFMVLSH 219
            |.:|||.:.  ..|.....|.|.........:..|.|:|..:.....:|:..|:..:|:|:.::.
Frog   175 GNVDYYSYD--NCDGPGVCGFDLHEGENVAWDQAGKYSTLLYAQRVNQILASHNPQQPIFIYVAF 237

  Fly   220 LAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLY 284
            .||||     |:|:|.|.:..:..:.:..||.||.|::.:|.:|.....|||..|..:||:|:..
Frog   238 QAVHT-----PLQSPREYIYPYRGMGNVARRKYAAMVTCMDAAVKNITRALKKYGYYSNSVIVFS 297

  Fly   285 SDNGAPTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAG 349
            ||||..|.    :.|||:|.||:|.:.||||:|..|.:.|||:|::...|...:|..||.|||..
Frog   298 SDNGGQTF----SGGSNWPLRGRKGTYWEGGVRGLGFVHSPLIKKKRRTSRALMHITDWYPTLVK 358

  Fly   350 AAGVSLPQDLPLDGINLWPMLSGNEEPKPRT-MIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQ 413
            .||.::.....|||.::|..:|..:| .||| ::|.:|.::..:.         :||..:|: ..
Frog   359 LAGGNISSAEGLDGYDVWGAISEGKE-SPRTEILHNIDPLYNLAK---------SGSLEEGQ-GV 412

  Fly   414 WLGELETNEDDPLGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEATETCPPIEGQN------P 472
            |            ..:.:..:...|.:.|.|:.|.            ::..||....|      .
Frog   413 W------------NTAVQASIRVKDFKLLTGDPGY------------SDWIPPQTLTNFPGSWWN 453

  Fly   473 LESHFKCEPLKAPCFFDLAKDPCERYNLAQMYPLQLQQLADELEQIRKTAIPSARVPHSDSRANP 537
            ||.|.. ...|:...|::..||.||::|:...|..:::|...|....:|||| .|.|..|.|.||
Frog   454 LERHTD-GARKSLWLFNITADPFERHDLSSSKPEVVKELLIRLGYYNRTAIP-VRYPAEDPRGNP 516

  Fly   538 TFHNGNWEWWNNTDTQSGSGTFSINLWLAMG 568
            ..:.|.|..|.:.|.......     |:..|
Frog   517 ELNGGAWGPWASEDDDDEEEN-----WIGKG 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	150/434 (35%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	145/408 (36%)
arsi	XP_002940132.1	4-S	49..481	CDD:293753	161/479 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	300	1.000	Domainoid score	I1405
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2217
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	1	1.000	-	-		FOG0000852
OrthoInspector	1	1.000	-	-		mtm9380
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X499
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970