DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7402 and arsia

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_002664306.1	Gene:	arsia / 100329483	ZFINID:	ZDB-GENE-140106-141	Length:	558	Species:	Danio rerio

Alignment Length:	529	Identity:	188/529 - (35%)
Similarity:	281/529 - (53%)	Gaps:	58/529 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPNLCTPSRATLLTGKYPIHT 91
            :|:|:.|:.||.|.||:.:|.:: |.||.:|.||..|:.|..:|:..:|||||:..:||:|.|||
Zfish    37 RPHIIFIMTDDQGFNDIGYHNTD-IHTPTLDRLAAAGVKLENYYIQPICTPSRSQFITGRYQIHT 100

  Fly    92 GMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHFGYYNGY 156
            |:||.:|.:.:|..||...|.:|:..::|||:||:||||||||:::|..||.|||:.:||...|.
Zfish   101 GLQHSIIRSRQPSCLPFGLRTLPQRLQEAGYATHMVGKWHLGFYKRDCLPTRRGFNTYFGSLTGS 165

  Fly   157 IDYYDHQVRMLDRNYSAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIEQHD-KSKPLFMVLSHL 220
            :|||.:  :..|.....|.|............|.|:|..:|...::|:..|| .|:|||:.||..
Zfish   166 VDYYTY--KSCDGPKVCGFDLHDGERVAWGQGGRYSTHLYTQRVRKILAAHDPSSQPLFIFLSFQ 228

  Fly   221 AVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYS 285
            ||||     |:|:|:|.|..:..:.:..||.||||:|::|::|.....||:..|...|::|...:
Zfish   229 AVHT-----PLQSPKEYVYPYRRMGNMFRRKYAGMVSAVDEAVRNVTYALRKYGYYKNTVIFFST 288

  Fly   286 DNGA-PTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAG 349
            |||. |..|     |||:|.||:|.:.||||:|..|.:.||||:.|..||...||..||.|||..
Zfish   289 DNGGQPLFG-----GSNWPLRGRKGTYWEGGVRGIGFVHSPLLRRRRRVSRALIHITDWYPTLMR 348

  Fly   350 AAGVSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQW 414
            .||.::.|...|||.::|..:|..:|.....::|.:|.::..:.:          .|.|..|..|
Zfish   349 LAGGNVSQAEGLDGFDMWDTISDGKESPRFEILHNIDPLYNAARH----------GSLKNGYGIW 403

  Fly   415 LGELETNEDDPLGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEATETCPP-IEGQNP-----L 473
                        ..:.:..|...|.:.|.||.|.            .:..|| :.|..|     |
Zfish   404 ------------NTAVQAAVRVGDWKLLTGNPGY------------GDWIPPQMLGNFPESWWSL 444

  Fly   474 ESHFKCEPLKAPCFFDLAKDPCERYNLAQMYPLQLQQLADELEQIRKTAIPSARVPHSDSRANPT 538
            |.|  .|..|:...|::|.||.||::||:..|..::||...|....:||:| .|.|..|.||:|:
Zfish   445 ERH--TEAKKSLWLFNVADDPYERFDLAERRPDVVKQLLARLSFYNRTAVP-VRYPSEDPRADPS 506

  Fly   539 FHNGNWEWW 547
            .:.|.|..|
Zfish   507 RNGGAWGPW 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	155/433 (36%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	150/409 (37%)
arsia	XP_002664306.1	AslA	37..471	CDD:225661	171/482 (35%)
arsia	XP_002664306.1	4-S	38..470	CDD:293753	170/480 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592862
Domainoid	1	1.000	294	0.414	Domainoid score	I1467
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2236
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	1	1.000	-	-		FOG0000852
OrthoInspector	1	1.000	-	-		mtm6503
orthoMCL	1	0.900	-	-		OOG6_100690
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X499
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.660