Protein Alignment CG7408 and ARSJ

DIOPT Version :10

• Sequence 1: NP_649020.1
• Gene: CG7408 / 39991
• FlyBaseID: FBgn0036765
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_078866.3
• Gene: ARSJ / 79642
• HGNCID: 26286
• Length: 599
• Species: Homo sapiens
• Alignment Length: 602
• Identity: 195/602 - (32%)
• Similarity: 280/602 - (46%)
• Gaps: 124/602 - (20%)

  Fly    11 ATSLLTGF-VLCIALSNGIVA--------------------------TSDKPNIIIIMADDLGFD 48
            |...|.|| :||: |:.|.::                          ::.:|::|.|:|||.||.
Human    26 AMGALAGFWILCL-LTYGYLSWGQALEEEEEGALLAQAGEKLEPSTTSTSQPHLIFILADDQGFR 89

  Fly    49 DVSFRGSNNFLTPNIDALAYSGVILNNLYVAPMCTPSRAALLTGKYPINTGMQHYVIVNDQPWGL 113
            ||.:.|| ...||.:|.||..||.|.|.||.|:|||||:..:||||.|:||:||.:|...||..|
Human    90 DVGYHGS-EIKTPTLDKLAAEGVKLENYYVQPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCL 153

  Fly   114 PLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQNKGY 178
            ||:..|:.:..:|.||.|.::||||||..::...||.||||...|.|....||||. |:..:.|.
Human   154 PLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGSLLGSGDYYTH-YKCDSPGM 217

  Fly   179 NGHDFRDSLKSTHDH-VGHYVTDLLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQA 242
            .|:|..::..:..|: .|.|.|.:.|....:.:..|   |.::|:||.:.:.|.|:     |:||
Human   218 CGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASH---NPTKPIFLYIAYQAVHS-----PLQA 274

  Fly   243 PAEEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDNGG-PTQGQHST 306
            |......:..|.|...|.||||:|.||:::.:|..||.......||||::.||||| ||.|
Human   275 PGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNGGQPTAG---- 335

  Fly   307 TASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLD 371
             .||:||||.|.:.|||.:|:...:.|...:..|:|.|:.::|.|..|||.:.|....|..:.||
Human   336 -GSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQIDEDIQLD 399

  Fly   372 GLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTRGK-----------------------WKVI 413
            |.::|..:..|..|...:|:|.||.       .||:.|                       ||::
Human   400 GYDIWETISEGLRSPRVDILHNIDP-------IYTKAKNGSWAAGYGIWNTAIQSAIRVQHWKLL 457

  Fly   414 SGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRNT--SVWLQLQQVSFGERNISELRDQSRIECP 476
            :|  |.| |..|:..:..|.:.|.....|.:..:|  |||
Human   458 TG--NPG-YSDWVPPQSFSNLGPNRWHNERITLSTGKSVW------------------------- 494

  Fly   477 DPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIFLDLWSRIQQFAKQAHPPNNKPGDPN 541
                            ||:|.|||.||.:|...|..  |...|..|:.||.|.|.|....|.||.
Human   495 ----------------LFNITADPYERVDLSNRYPG--IVKKLLRRLSQFNKTAVPVRYPPKDPR 541

  Fly   542 CDPRFYHNEW-TWWQDE 557
            .:||.....| .|:::|
Human   542 SNPRLNGGVWGPWYKEE 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_649020.1	4-S	35..423	CDD:293753	152/412 (37%)
ARSJ	NP_078866.3	4-S	76..509	CDD:293753	169/498 (34%)
		DUF4976	<495..>533	CDD:419068	17/39 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	531..599		9/28 (32%)