DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7408 and Sulf2

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001239508.1	Gene:	Sulf2 / 72043	MGIID:	1919293	Length:	908	Species:	Mus musculus

Alignment Length:	528	Identity:	120/528 - (22%)
Similarity:	201/528 - (38%)	Gaps:	114/528 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYV-APMCTPSRAALLTGKYPIN 97
            :||||:::.||   .||.. ||...:......:...|....|.:| .|||.|||:::|||||..|
Mouse    76 RPNIILVLTDD---QDVEL-GSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHN 136

  Fly    98 TGMQHYVIVNDQ-----PWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHL 157
                |....|::     .|.......|.|......||||:..||:   |::.|.:....|:...:
Mouse   137 ----HNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY---LNEYNGSYVPPGWKEWV 194

  Fly   158 GYLGAYVDYYTQSYEQQNKGYNGHDFRDSLKSTH--DHVGHYVTDLLTDAAVKEIEDHGSKNSSQ 220
            |.|            :.::.||....|:.:|..|  |:...|:|||:|:.:|............:
Mouse   195 GLL------------KNSRFYNYTLCRNGVKEKHGSDYSTDYLTDLITNDSVSFFRTSKKMYPHR 247

  Fly   221 PLFLLLNHLAPHAANDDDPM-----------------QAPAEE---VSRFEYISNKTHRYYAAMV 265
            |:.::::|.|||...|..|.                 .||..:   :.|:.......|..:..|:
Mouse   248 PVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNML 312

  Fly   266 SR--------LDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWE 322
            .|        :|.|:.::.|.|.....|.|:.||:.:|:     |.|   ...:.|...|:.|:|
Mouse   313 QRKRLQTLMSVDDSMETIYDMLVETGELDNTYILYTADH-----GYH---IGQFGLVKGKSMPYE 369

  Fly   323 GALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVE 387
            ..:|....:.....| .||:....:...||.||:...||:  |....:||
Mouse   370 FDIRVPFYVRGPNVE-AGSLNPHIVLNIDLAPTILDIAGL--DIPADMDG--------------- 416

  Fly   388 REIVHVIDED--VAEPHLSYTRGKWKVISGTTNQGLYD-GWLGH-RETSEVD-------PRAVEY 441
            :.|:.::|.:  |...||......|:      :..|.: |.|.| ||..:|:       |:....
Mouse   417 KSILKLLDSERPVNRFHLKKKLRVWR------DSFLVERGKLLHKREGDKVNAQEENFLPKYQRV 475

  Fly   442 EELVRNTSVWLQLQQVSFGERNISELRDQSRIECPDPATGVKPCLPLEGPCLFDIEADPCERSNL 506
            ::|.:........:|:.            .:.:|.:.|:|.......:||..|.........|||
Mouse   476 KDLCQRAEYQTACEQLG------------QKWQCVEDASGTLKLHKCKGPMRFGGGGGSRALSNL 528

  Fly   507 YAEYQNST 514
            ..:|...:
Mouse   529 VPKYDGQS 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	101/429 (24%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	101/425 (24%)
Sulf2	NP_001239508.1	AslA	76..>420	CDD:225661	94/392 (24%)
		G6S	76..418	CDD:293766	94/390 (24%)
		DUF3740	573..699	CDD:289325
		ALP_like	<787..836	CDD:304875
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847539
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740