Protein Alignment CG7408 and SGSH

DIOPT Version :10

• Sequence 1: NP_649020.1
• Gene: CG7408 / 39991
• FlyBaseID: FBgn0036765
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_000190.1
• Gene: SGSH / 6448
• HGNCID: 10818
• Length: 502
• Species: Homo sapiens
• Alignment Length: 606
• Identity: 129/606 - (21%)
• Similarity: 217/606 - (35%)
• Gaps: 188/606 - (31%)

  Fly    21 CIALSNGIVATSDKP-NIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYVA-PMCT 83
            |.||...:.....:| |.::::|||.||:..::..| ...||::||||...::..|.:.: ..|:
Human     8 CCALLLVLGLCRARPRNALLLLADDGGFESGAYNNS-AIATPHLDALARRSLLFRNAFTSVSSCS 71

  Fly    84 PSRAALLTGKYPINTGMQ------HYVIVNDQPWGLPLNETTMAEIFRENGYRTSLLGKWHLG-- 140
            ||||:||||......||.      |:....|:...|||       :..:.|.||.::||.|:|
Human    72 PSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPL-------LLSQAGVRTGIIGKKHVGPE 129

  Fly   141 ---------------------------LSQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQNKGY 178
                                       |..|.|..|:.  ||......|:.|.:...:.|...|.
Human   130 TVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQD--DRPFFLYVAFHDPHRCGHSQPQYGT 192

  Fly   179 NGHDFRDSLKSTHDHVGHYVTDLLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAP 243
            ....|.:.                 ::.:..|.| .:..:..||.:|:.:..|:         .|
Human   193 FCEKFGNG-----------------ESGMGRIPD-WTPQAYDPLDVLVPYFVPN---------TP 230

  Fly   244 AEEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTA 308
            |   :|.:..:..|      .|.|:|:.||.|:..|....:|.:::::|.||||.|
Human   231 A---ARADLAAQYT------TVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIP--------- 277

  Fly   309 SNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPA------ 367
              :| .|:.|..|.|.............:|.|.|.:..:.:.||.||:.....| |.|:
Human   278 --FP-SGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSI-PYPSYAIFGS 338

  Fly   368 --LHLDGLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTRGKWKVISGTTNQGLYDGWLGHRE 430
              :||.|.:|..||:                  |||       .|..:.|:.:.        |..
Human   339 KTIHLTGRSLLPALE------------------AEP-------LWATVFGSQSH--------HEV 370

  Fly   431 TSEVDPRAVEYE--ELVRNTSVWLQ----------------LQQVSFGE-----RNISELRDQSR 472
            |.....|:|::.  .||.|.:..:.                |.:.:.|:     :::.....::|
Human   371 TMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRAR 435

  Fly   473 IECPDPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIFLDLWSRIQQFAKQAHPP---- 533
            .|                  |:|...||.|..||..:.:.:.:...|..::.::..:.|.|
Human   436 WE------------------LYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCA 482

  Fly   534 ----NNKPGDPNCDPRFYHNE 550
                ..:...|.|.|  .|||
Human   483 PDGVLEEKLSPQCQP--LHNE 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_649020.1	4-S	35..423	CDD:293753	99/432 (23%)
SGSH	NP_000190.1	SGSH	24..472	CDD:293751	117/557 (21%)