DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7408 and SGSH

DIOPT Version :9

Sequence 1:NP_001163462.1 Gene:CG7408 / 39991 FlyBaseID:FBgn0036765 Length:585 Species:Drosophila melanogaster
Sequence 2:NP_000190.1 Gene:SGSH / 6448 HGNCID:10818 Length:502 Species:Homo sapiens


Alignment Length:606 Identity:129/606 - (21%)
Similarity:217/606 - (35%) Gaps:188/606 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 CIALSNGIVATSDKP-NIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYVA-PMCT 83
            |.||...:.....:| |.::::|||.||:..::..| ...||::||||...::..|.:.: ..|:
Human     8 CCALLLVLGLCRARPRNALLLLADDGGFESGAYNNS-AIATPHLDALARRSLLFRNAFTSVSSCS 71

  Fly    84 PSRAALLTGKYPINTGMQ------HYVIVNDQPWGLPLNETTMAEIFRENGYRTSLLGKWHLG-- 140
            ||||:||||......||.      |:....|:...|||       :..:.|.||.::||.|:|  
Human    72 PSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPL-------LLSQAGVRTGIIGKKHVGPE 129

  Fly   141 ---------------------------LSQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQNKGY 178
                                       |..|.|..|:.  ||......|:.|.:...:.|...|.
Human   130 TVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQD--DRPFFLYVAFHDPHRCGHSQPQYGT 192

  Fly   179 NGHDFRDSLKSTHDHVGHYVTDLLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAP 243
            ....|.:.                 ::.:..|.| .:..:..||.:|:.:..|:         .|
Human   193 FCEKFGNG-----------------ESGMGRIPD-WTPQAYDPLDVLVPYFVPN---------TP 230

  Fly   244 AEEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTA 308
            |   :|.:..:..|      .|.|:|:.||.|:..|....:|.:::::|.||||.|         
Human   231 A---ARADLAAQYT------TVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIP--------- 277

  Fly   309 SNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPA------ 367
              :| .|:.|..|.|.............:|.|.|.:..:.:.||.||:.....| |.|:      
Human   278 --FP-SGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSI-PYPSYAIFGS 338

  Fly   368 --LHLDGLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTRGKWKVISGTTNQGLYDGWLGHRE 430
              :||.|.:|..||:                  |||       .|..:.|:.:.        |..
Human   339 KTIHLTGRSLLPALE------------------AEP-------LWATVFGSQSH--------HEV 370

  Fly   431 TSEVDPRAVEYE--ELVRNTSVWLQ----------------LQQVSFGE-----RNISELRDQSR 472
            |.....|:|::.  .||.|.:..:.                |.:.:.|:     :::.....::|
Human   371 TMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRAR 435

  Fly   473 IECPDPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIFLDLWSRIQQFAKQAHPP---- 533
            .|                  |:|...||.|..||..:.:.:.:...|..::.::..:.|.|    
Human   436 WE------------------LYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCA 482

  Fly   534 ----NNKPGDPNCDPRFYHNE 550
                ..:...|.|.|  .|||
Human   483 PDGVLEEKLSPQCQP--LHNE 501

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7408NP_001163462.1 AslA 31..425 CDD:225661 99/438 (23%)
4-S 35..423 CDD:293753 99/432 (23%)
SGSHNP_000190.1 SGSH 24..472 CDD:293751 117/557 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG3119
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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