DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7408 and arsk

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001070625.1	Gene:	arsk / 562412	ZFINID:	ZDB-GENE-060929-332	Length:	523	Species:	Danio rerio

Alignment Length:	592	Identity:	123/592 - (20%)
Similarity:	204/592 - (34%)	Gaps:	183/592 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLTGFVLCIALSNGIV-----ATSDKPNIIIIMADDLGFDD-VSFRGSNNFL-TPNIDALAYSG- 70
            :|..|||.|...|...     .:.|:|||::||:|  .||. ::|:..|..: .|.|:.:...|
Zfish     1 MLRVFVLLIFNVNAYCMYLNWTSHDRPNIVMIMSD--AFDGRLTFQPGNKVVQLPYINYMRELGS 63

  Fly    71 VILNNLYVAPMCTPSRAALLTGKYPINTGMQHYVIVNDQPWG----LPLNETTMAEIFRENGYRT 131
            |.||:...:|:|.|||||:.:|::...|          |.|.    |..|.||..:..|::||.|
Zfish    64 VFLNSYTNSPICCPSRAAMWSGQFVHLT----------QSWNNNKCLHPNATTWMDDLRKSGYHT 118

  Fly   132 SLLGKWHLGLSQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQNKGYNGHDFRDSLKSTHDHVGH 196
            ..:||........:.:.....:.|.:.:|                      .|...:...|.||.
Zfish   119 HSMGKLDYTSGHHSVSNRVEAWTRDVPFL----------------------LRQEGRPVTDLVGD 161

  Fly   197 YVTD-------LLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDD---------------- 238
            ..|.       .:|||||:.|. :.:.:.:||..|.|....||....|.
Zfish   162 ASTKRVMIKDWTITDAAVQWIR-NTTASLTQPFALYLGLNLPHPYRTDSLGPTAGGSTFRTSPYW 225

  Fly   239 -----------PMQAPAEEVSRFEYISNKT---------------HRYYAAMVSRLDKSVGSVID 277
                       |.....:::...:|.|..|               ..:|.||.:..|..:|.|:.
Zfish   226 LNKVSYNQVSVPKWLRFKDMHPVDYYSTVTKNCSGHFTEEEIRNIRAFYYAMCAETDGMLGEVMA 290

  Fly   278 ALARQEMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSV 342
            ||.....|..:::||.||:|.... :|.        :..|.|.:||:......|..... :.|..
Zfish   291 ALRDTGSLNKTVVLFTSDHGDLAM-EHR--------QFYKMSMFEGSSHVPLLIMGPGV-KSGFE 345

  Fly   343 WKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTR 407
            ....:.:.|:.||:...||:.     ...||:..|.:..    :.|..:|     .||||.::..
Zfish   346 VSLPVSLVDIYPTVLDLAGVP-----QTGGLSGHSLIPL----ISRVSIH-----SAEPHPAWAF 396

  Fly   408 GKWKVISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRNTSVWL----QLQQVSFGERNISELR 468
            .                               ||.....|||.::    :.:.:::
Zfish   397 S-------------------------------EYHGCNANTSTYMLRIAEWKYIAY--------- 421

  Fly   469 DQSRIECPDPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIFLDLWSR----IQQFAKQ 529
                      |.|:.  :|   |.||::..|..|..|:.:::.:....||...|    ....:|.
Zfish   422 ----------ADGLN--VP---PQLFNLSKDESELRNIASQFPDVCQDLDKLLRSIVDYPSVSKS 471

  Fly   530 AHPPNNK 536
            .|..|.:
Zfish   472 VHRYNKQ 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	97/449 (22%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	96/443 (22%)
arsk	NP_001070625.1	AslA	25..445	CDD:225661	111/533 (21%)
arsk	NP_001070625.1	ARSK	27..439	CDD:293781	108/525 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592893
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740