Protein Alignment CG7408 and SULF2

DIOPT Version :9

• Sequence 1: NP_001163462.1
• Gene: CG7408 / 39991
• FlyBaseID: FBgn0036765
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001373981.1
• Gene: SULF2 / 55959
• HGNCID: 20392
• Length: 871
• Species: Homo sapiens
• Alignment Length: 625
• Identity: 136/625 - (21%)
• Similarity: 229/625 - (36%)
• Gaps: 170/625 - (27%)

  Fly    34 KPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYV-APMCTPSRAALLTGKYPIN 97
            :||||:::.||   .||.. ||...:......:...|....|.:| .|||.|||:::|||||..|
Human    43 RPNIILVLTDD---QDVEL-GSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHN 103

  Fly    98 TGMQHYVIVNDQ-----PWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHL 157
                |....|::     .|.......|.|......||||:..||:   |::.|.:....|:...:
Human   104 ----HNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY---LNEYNGSYVPPGWKEWV 161

  Fly   158 GYLGAYVDYYTQSYEQQNKGYNGHDFRDSLKSTH--DHVGHYVTDLLTDAAVKEIEDHGSKNSSQ 220
            |.|            :.::.||....|:.:|..|  |:...|:|||:|:.:|............:
Human   162 GLL------------KNSRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHR 214

  Fly   221 PLFLLLNHLAPHAANDDDPM-----------------QAPAEE---VSRFEYISNKTHRYYAAMV 265
            |:.::::|.|||...|..|.                 .||..:   :.|:.......|..:..|:
Human   215 PVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNML 279

  Fly   266 SR--------LDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWE 322
            .|        :|.|:.::.:.|.....|.|:.|::.:|:     |.|   ...:.|...|:.|:|
Human   280 QRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADH-----GYH---IGQFGLVKGKSMPYE 336

  Fly   323 GALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVE 387
            ..:|....:.....| .|.:....:...||.||:...||:  |....:||
Human   337 FDIRVPFYVRGPNVE-AGCLNPHIVLNIDLAPTILDIAGL--DIPADMDG--------------- 383

  Fly   388 REIVHVIDED--VAEPHLSYTRGKWKVISGTTNQGLYD-GWLGH-RETSEVD-------PRAVEY 441
            :.|:.::|.:  |...||......|:      :..|.: |.|.| |:..:||       |:....
Human   384 KSILKLLDTERPVNRFHLKKKMRVWR------DSFLVERGKLLHKRDNDKVDAQEENFLPKYQRV 442

  Fly   442 EELVRNTSVWLQLQQVSFGERNISELRDQSRIECPDPATGVKPCLPLEGP-------CLFDI--- 496
            ::|.:........:|:.            .:.:|.:.|||.......:||       .|.::
Human   443 KDLCQRAEYQTACEQLG------------QKWQCVEDATGKLKLHKCKGPMRLGGSRALSNLVPK 495

  Fly   497 ------EADPCE-----------RSNLY-----AEYQNS----TIFLDLWSRIQQ--FAKQAHPP 533
                  ||..|:           |..|:     |.|..|    ::.:::..|:..  ....|.|.
Human   496 YYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSVAIEVDGRVYHVGLGDAAQPR 560

  Fly   534 N----NKPGDPNCDPRFYHNEWTWWQDEK--ASSSGTIGV 567
            |    :.||.|..            ||:|  ...|||.|:
Human   561 NLTKRHWPGAPED------------QDDKDGGDFSGTGGL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	98/429 (23%)
		4-S	35..423	CDD:293753	98/425 (23%)
SULF2	NP_001373981.1	G6S	43..385	CDD:293766	91/390 (23%)
		DUF3740	529..662	CDD:403667	17/72 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	560..588		10/39 (26%)
		ALP_like	<750..799	CDD:419962

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157132
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740