Protein Alignment CG7408 and ARSL

DIOPT Version :10

• Sequence 1: NP_649020.1
• Gene: CG7408 / 39991
• FlyBaseID: FBgn0036765
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001269557.1
• Gene: ARSL / 415
• HGNCID: 719
• Length: 614
• Species: Homo sapiens
• Alignment Length: 616
• Identity: 159/616 - (25%)
• Similarity: 227/616 - (36%)
• Gaps: 144/616 - (23%)

  Fly    19 VLCIALSNGIVATSD----KPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGV-ILNNLYV 78
            :|.:.||....|:||    :|||:::||||||..|:...|:|...|||||.||..|| :..::..
Human    43 MLAVLLSLAPSASSDISASRPNILLLMADDLGIGDIGCYGNNTMRTPNIDRLAEDGVKLTQHISA 107

  Fly    79 APMCTPSRAALLTGKYPINTGMQHYVIVNDQPW-----GLPLNETTMAEIFRENGYRTSLLGKWH 138
            |.:|||||||.|||:||:.:||...:......|     |||.||||.|:|.:|.||.|.|:||||
Human   108 ASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYATGLIGKWH 172

  Fly   139 LGL-----SQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQNKGYNGHDFRDSL----------- 187
            |||     |.....|...|||...|...:.:....: :|...|..|.....:.|
Human   173 LGLNCESASDHCHHPLHHGFDHFYGMPFSLMGDCAR-WELSEKRVNLEQKLNFLFQVLALVALTL 236

  Fly   188 ---KSTH-----------------------DHVG-------------HYVTD------LLTDAAV 207
               |.||                       ..||             |.:|:      ..|...:
Human   237 VAGKLTHLIPVSWMPVIWSALSAVLLLASSYFVGALIVHADCFLMRNHTITEQPMCFQRTTPLIL 301

  Fly   208 KEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAPAEEVSRFEYISNKTHRYYAAMVSRLDKSV 272
            :|:.....:|...|..|.::.|..|.     |:      ::...::....|..|...|..:|..|
Human   302 QEVASFLKRNKHGPFLLFVSFLHVHI-----PL------ITMENFLGKSLHGLYGDNVEEMDWMV 355

  Fly   273 GSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTT---ASNYPLRGQKN-SPWEGALRSSAAIWS 333
            |.::|.|..:.:..:::|.|.||:||..:.|...|   ..|...:|.|. ..|||.:|.......
Human   356 GRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEGGIRVPGIFRW 420

  Fly   334 TEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVERE-IVHVIDE- 396
            ......|.|..:...:.|:.||:...||........:||.:|...|....:..:.| ::|..:.
Human   421 PGVLPAGRVIGEPTSLMDVFPTVVRLAGGEVPQDRVIDGQDLLPLLLGTAQHSDHEFLMHYCERF 485

  Fly   397 -DVAEPHLSYTRGKWKVISGTTNQGLYDGWLGHRETSEVDPRAVE--YEELVRNTSVWLQLQQVS 458
             ..|..|.......|||               |..|....|....  |...|          ...
Human   486 LHAARWHQRDRGTMWKV---------------HFVTPVFQPEGAGACYGRKV----------CPC 525

  Fly   459 FGERNISELRDQSRIECPDPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIFLDLWSRI 523
            |||:.:..          ||            |.|||:..||.|...|..  .:..:|..:..|:
Human   526 FGEKVVHH----------DP------------PLLFDLSRDPSETHILTP--ASEPVFYQVMERV 566

  Fly   524 QQFAKQAHPPNNKPGDPNCDPRFYHNEWTWW 554
            || |...|.....|.....|.  ..|.|..|
Human   567 QQ-AVWEHQRTLSPVPLQLDR--LGNIWRPW 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_649020.1	4-S	35..423	CDD:293753	124/461 (27%)
ARSL	NP_001269557.1	ALP_like	62..585	CDD:474031	149/584 (26%)