Protein Alignment CG7408 and STS

DIOPT Version :9

• Sequence 1: NP_001163462.1
• Gene: CG7408 / 39991
• FlyBaseID: FBgn0036765
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001307679.1
• Gene: STS / 412
• HGNCID: 11425
• Length: 590
• Species: Homo sapiens
• Alignment Length: 656
• Identity: 154/656 - (23%)
• Similarity: 238/656 - (36%)
• Gaps: 208/656 - (31%)

  Fly    18 FVLCIALSNGIVATSDKPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGV-ILNNLYVAPM 81
            |:|...|.......:.:||||::||||||..|....|:....|||||.||..|| :..:|..:|:
Human    17 FLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPL 81

  Fly    82 CTPSRAALLTGKYPINTGMQHY-----VIVNDQPWGLPLNETTMAEIFRENGYRTSLLGKWHLGL 141
            |||||||.:||:||:.:||..:     .:......|||.:|.|.|::.::.||.|:|:||||||:
Human    82 CTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGM 146

  Fly   142 SQRNFT-----PTERGFDRHLG------------------------------------------- 158
            |..:.|     |...||:...|
Human   147 SCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTTGFKRLVFLPLQIVGVTLLTLAALN 211

  Fly   159 -------------------------YLGAYVDYY-------TQSYE--QQNKGYNGHDFRDSLKS 189
                                     :|| ::.|:       .::||  ||...|:.
Human   212 CLGLLHVPLGVFFSLLFLAALILTLFLG-FLHYFRPLNCFMMRNYEIIQQPMSYDN--------- 266

  Fly   190 THDHVGHYVTDLLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAPAEEVSRFEYIS 254
                    :|..||..|.:.|:    :|:..|..|:|::|..|.|           ..|..::..
Human   267 --------LTQRLTVEAAQFIQ----RNTETPFLLVLSYLHVHTA-----------LFSSKDFAG 308

  Fly   255 NKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHST----TASNYPLRG 315
            ...|..|...|..:|.|||.:::.|....:..:::|.|.||.|...:...|.    ..||...:|
Human   309 KSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKG 373

  Fly   316 QKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIG----------DLLPTLAAAAGIS-PDPALH 369
            .|.:.|||.:|....:          .|.:.|..|          |:.||:|..||.. |:..:
Human   374 GKANNWEGGIRVPGIL----------RWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRI- 427

  Fly   370 LDGLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTRGKWKVISGTTNQGLYDGWLGHRETSEV 434
            :||.:|...|:...:..:.|.:.    .....:|:..|                 |  |.:.|
Human   428 IDGRDLMPLLEGKSQRSDHEFLF----HYCNAYLNAVR-----------------W--HPQNS-- 467

  Fly   435 DPRAVEYEELVRNTSVWLQLQQVSFGERNISELRDQSRIECPDPATGVKPCLPL-----EGPCLF 494
                         ||:|    :..|...|.:.:......     ||.|..|...     :.|.||
Human   468 -------------TSIW----KAFFFTPNFNPVGSNGCF-----ATHVCFCFGSYVTHHDPPLLF 510

  Fly   495 DIEADPCERSNLYAEYQNSTIFLDLWSRIQQFAKQAHPPNNKPGDPNCDPRFYHNEWTW--WQDE 557
            ||..||.||:.|..  .:...|.:: .::.|.|...|....    |....:|..|.:.|  |...
Human   511 DISKDPRERNPLTP--ASEPRFYEI-LKVMQEAADRHTQTL----PEVPDQFSWNNFLWKPWLQL 568

  Fly   558 KASSSG 563
            ...|:|
Human   569 CCPSTG 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	118/496 (24%)
		4-S	35..423	CDD:293753	118/490 (24%)
STS	NP_001307679.1	AslA	30..555	CDD:225661	145/622 (23%)
		ES	33..557	CDD:293778	146/621 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157203
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740