DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7408 and sulf2a

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_005169326.1	Gene:	sulf2a / 393910	ZFINID:	ZDB-GENE-040426-759	Length:	874	Species:	Danio rerio

Alignment Length:	495	Identity:	117/495 - (23%)
Similarity:	191/495 - (38%)	Gaps:	113/495 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ATSLLTGFVLCIALSNGIVATSD--------------KPNIIIIMADDLGFDDVSFRGSNNFLTP 61
            ||.||...:..|.||:|....|.              :||:|:|:.||   .|:.. ||...:..
Zfish     8 ATLLLVFILTFICLSDGSTYLSGQRQRSRLQRDRRNVRPNMILILTDD---QDIEL-GSMQAMNK 68

  Fly    62 NIDALAYSGVILNNLY-VAPMCTPSRAALLTGKYPINTGMQHYVIVNDQ-----PWGLPLNETTM 120
            ....:...|...:|.: ..|||.|||:.:|||||..|    |:...|::     .|.......|.
Zfish    69 TKRIMMQGGTHFSNAFATTPMCCPSRSTILTGKYVHN----HHTYTNNENCSSPSWQAHHEPHTF 129

  Fly   121 AEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHLGYLGAYVDYYTQSY---EQQNKGYNGHD 182
            |.....:||||:..||:   |::               |.|:||....:.:   .:.::.||...
Zfish   130 AVHLNNSGYRTAFFGKY---LNE---------------YNGSYVPPGWREWVALVKNSRFYNYTL 176

  Fly   183 FRDSLKSTH--DHVGHYVTDLLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPM----- 240
            .|:.::..|  .:...|:||::|:.::............:|:.::|:|.|||...|..|.
Zfish   177 CRNGIREKHGTQYPKDYLTDVITNDSINYFRMSKRMYPHRPVMMVLSHAAPHGPEDAAPQYSSAF 241

  Fly   241 ------------QAPAEE---VSRFEYISNKTHRYYAAMVSR--------LDKSVGSVIDALARQ 282
                        .||..:   :.|:.......|..:..|:.|        :|.||..|.:.|...
Zfish   242 PNASQHITPSYNHAPNPDKHWILRYTGPMKPVHMQFTNMLQRRRLQTLLSVDDSVEKVYNMLVET 306

  Fly   283 EMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQI 347
            ..|.|:.|:::||:     |.|   ...:.|...|:.|:|..:|....:.....| .|::....:
Zfish   307 GELDNTYIIYMSDH-----GYH---IGQFGLVKGKSMPYEFDIRIPFYVRGPNVE-AGAINPHIV 362

  Fly   348 YIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTRGK-WK 411
            ...||.|||...|||  |....:||.::...|:     .||.:     ......| ||.:.| |:
Zfish   363 LNTDLAPTLLDMAGI--DIPQDMDGKSILKLLE-----TERPV-----NSFTRFH-SYKKAKLWR 414

  Fly   412 ----VISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRN 447
                |..|.....|.||       .||:..::...:.||:
Zfish   415 DSFLVERGKPLHKLADG-------KEVEQNSLPKYQRVRD 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	104/451 (23%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	102/431 (24%)
sulf2a	XP_005169326.1	G6S	45..387	CDD:293766	91/378 (24%)
		DUF3740	541..670	CDD:289325
		ALP_like	<758..807	CDD:304875
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592914
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740