Protein Alignment CG7408 and ARSH

DIOPT Version :10

• Sequence 1: NP_649020.1
• Gene: CG7408 / 39991
• FlyBaseID: FBgn0036765
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001011719.1
• Gene: ARSH / 347527
• HGNCID: 32488
• Length: 562
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 148/569 - (26%)
• Similarity: 212/569 - (37%)
• Gaps: 157/569 - (27%)

  Fly    34 KPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGV-ILNNLYVAPMCTPSRAALLTGKYPIN 97
            :|||:::||||||..|:...|:|:..|||||.||..|| :..:|..|.||||||||.|||:|||.
Human     6 RPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGRYPIR 70

  Fly    98 TGM-QHYVIVNDQPW-----GLPLNETTMAEIFRENGYRTSLLGKWHLGLS--QRN---FTPTER 151
            :|| ..|.:.....|     |||.||||.|::.:..||||.|:||||||||  .||   :.|...
Human    71 SGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRNDHCYHPLNH 135

  Fly   152 GFDRHLGY-LGAYVDYYTQSYEQQNK--------------------------------------- 176
            ||....|. .|...|.......:.::
Human   136 GFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFLLLIPKFARWFSVPWKVIFVF 200

  Fly   177 ----------GYNGHDFRDS----LKSTHDHV-----GHYVTDLLTDAAVKEIEDHGSKNSSQPL 222
                      .|:.:.|...    |...|:.:     ...|..|:...|:..||    :...:|.
Human   201 ALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEKVASLMLKEALAFIE----RYKREPF 261

  Fly   223 FLLLNHLAPHAANDDDPMQAPAEEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQN 287
            .|..:.|..|.     |:      :|:.:::....:..|...|..:|..||.::|||.::.:..:
Human   262 LLFFSFLHVHT-----PL------ISKKKFVGRSKYGRYGDNVEEMDWMVGKILDALDQERLANH 315

  Fly   288 SIILFLSDNGG---PTQGQHSTTASNYPLRGQKN-SPWEGALRSSAAI-WSTEFERLGSVWKQQI 347
            :::.|.|||||   |..|.......|...:|.|. ..|||.:|..... |.:..| .|.|..:..
Human   316 TLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPSVLE-AGRVINEPT 379

  Fly   348 YIGDLLPTLAAAAG--ISPDPALHLDGLNLWSALKYGYESVEREI--------VHVIDEDVAEPH 402
            .:.|:.|||:...|  :|.|..  :||.||...|:......:.|.        :|.:
Human   380 SLMDIYPTLSYIGGGILSQDRV--IDGQNLMPLLEGRASHSDHEFLFHYCGVYLHTV-------- 434

  Fly   403 LSYTRGKWKVISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRNTSVWLQLQQVSFGERNISEL 467
                  :|......|      .|..|..|.:..|...                ...:|....|
Human   435 ------RWHQKDCAT------VWKAHYVTPKFYPEGT----------------GACYGSGICS-- 469

  Fly   468 RDQSRIECPDPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIF 516
                   |....|...|      |.||||..||.|...|..:  |..:|
Human   470 -------CSGDVTYHDP------PLLFDISRDPSEALPLNPD--NEPLF 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_649020.1	4-S	35..423	CDD:293753	128/473 (27%)
ARSH	NP_001011719.1	ALP_like	6..530	CDD:474031	148/569 (26%)