DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7408 and Sulf2

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001030099.1	Gene:	Sulf2 / 311642	RGDID:	1305078	Length:	875	Species:	Rattus norvegicus

Alignment Length:	528	Identity:	120/528 - (22%)
Similarity:	202/528 - (38%)	Gaps:	115/528 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYV-APMCTPSRAALLTGKYPIN 97
            :||||:::.||   .||.. ||...:......:...|....|.:| .|||.|||:::|||||..|
  Rat    43 RPNIILVLTDD---QDVEL-GSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHN 103

  Fly    98 TGMQHYVIVNDQ-----PWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHL 157
                |....|::     .|.......|.|......||||:..||:   |::.|.:....|:...:
  Rat   104 ----HNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY---LNEYNGSYVPPGWKEWV 161

  Fly   158 GYLGAYVDYYTQSYEQQNKGYNGHDFRDSLKSTH--DHVGHYVTDLLTDAAVKEIEDHGSKNSSQ 220
            |.|            :.::.||....|:.:|..|  |:...|:|||:|:.:|............:
  Rat   162 GLL------------KNSRFYNYTLCRNGMKEKHGSDYSTDYLTDLITNDSVSFFRTSKKMYPHR 214

  Fly   221 PLFLLLNHLAPHAANDDDPM-----------------QAPAEE---VSRFEYISNKTHRYYAAMV 265
            |:.::::|.|||...|..|.                 .||..:   :.|:.......|..:..|:
  Rat   215 PVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNML 279

  Fly   266 SR--------LDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWE 322
            .|        :|.|:.::.|.|.....|.|:.|::.:|:     |.|   ...:.|...|:.|:|
  Rat   280 QRKRLQTLMSVDDSMETIYDMLVETGELDNTYIVYTADH-----GYH---IGQFGLVKGKSMPYE 336

  Fly   323 GALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVE 387
            ..:|....:.....| .||:....:...||.||:...||:  |....:||
  Rat   337 FDIRVPFYVRGPSVE-AGSLNPHIVLNIDLAPTILDIAGL--DIPADMDG--------------- 383

  Fly   388 REIVHVIDED--VAEPHLSYTRGKWKVISGTTNQGLYD-GWLGH-RETSEVD-------PRAVEY 441
            :.|:.::|.:  |...||......|:      :..|.: |.|.| ||..:|:       |:....
  Rat   384 KSILKLLDSERPVNRFHLKKKLRVWR------DSFLVERGKLLHKREGDKVNAQEENFLPKYQRV 442

  Fly   442 EELVRNTSVWLQLQQVSFGERNISELRDQSRIECPDPATGVKPCLPLEGPCLFDIEADPCERSNL 506
            ::|.:........:|:.            .:.:|.:.|:|.......:||..|....|.. .|||
  Rat   443 KDLCQRAEYQTACEQLG------------QKWQCVEDASGALKLHKCKGPVRFGGGGDRA-LSNL 494

  Fly   507 YAEYQNST 514
            ..:|...:
  Rat   495 VPKYDGQS 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	100/429 (23%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	100/425 (24%)
Sulf2	NP_001030099.1	G6S	43..385	CDD:293766	93/390 (24%)
		DUF3740	533..666	CDD:403667
		ALP_like	<754..803	CDD:419962
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351091
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740