DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7408 and Arsj

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001041352.1	Gene:	Arsj / 311013	RGDID:	1307640	Length:	597	Species:	Rattus norvegicus

Alignment Length:	562	Identity:	189/562 - (33%)
Similarity:	271/562 - (48%)	Gaps:	95/562 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ATSDKPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYVAPMCTPSRAALLTGKY 94
            |.:.:|::|.|:|||.||.||.:.|| ...||.:|.||..||.|.|.||.|:|||||:..:||||
  Rat    69 AVTSQPHLIFILADDQGFRDVGYHGS-EIKTPTLDKLAAEGVKLENYYVQPICTPSRSQFITGKY 132

  Fly    95 PINTGMQHYVIVNDQPWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHLGY 159
            .|:||:||.:|...||..|||:..|:.:..:|.||.|.::||||||..:::..||:||||...|.
  Rat   133 QIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKDCMPTKRGFDTFFGS 197

  Fly   160 LGAYVDYYTQSYEQQNKGYNGHDFRDSLKSTHDH-VGHYVTDLLTDAAVKEIEDHGSKNSSQPLF 223
            |....||||. |:..:.|..|:|..::..:..|: .|.|.|.:.|....:.:..|   :.::|||
  Rat   198 LLGSGDYYTH-YKCDSPGVCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASH---DPTKPLF 258

  Fly   224 LLLNHLAPHAANDDDPMQAPAEEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNS 288
            |.:.:.|.|:     |:|||......:..|.|...|.||||:|.||:::.:|..||.|.....||
  Rat   259 LYVAYQAVHS-----PLQAPGRYFEHYRSIININRRRYAAMLSCLDEAIHNVTLALKRYGFYNNS 318

  Fly   289 IILFLSDNGG-PTQGQHSTTASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIGDL 352
            ||::.||||| ||.|     .||:||||.|.:.|||.:|:...:.|...:..|:|.|:.::|.|.
  Rat   319 IIIYSSDNGGQPTAG-----GSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDW 378

  Fly   353 LPTLAAAAGISPDPALHLDGLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTRGK-------- 409
            .|||.:.|....|..:.|||.::|..:..|..|...:|:|.||.       .||:.|
  Rat   379 YPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDP-------IYTKAKNGSWAAGY 436

  Fly   410 ---------------WKVISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRNT--SVWLQLQQV 457
                           ||:::|  |.| |..|:..:..|.:.|.....|.:..:|  |:|
  Rat   437 GIWNTAIQSAIRVQHWKLLTG--NPG-YSDWVPPQAFSNLGPNRWHNERITLSTGKSIW------ 492

  Fly   458 SFGERNISELRDQSRIECPDPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIFLDLWSR 522
                                               ||:|.|||.||.:|.:.|..  |...|..|
  Rat   493 -----------------------------------LFNITADPYERVDLSSRYPG--IVKKLLRR 520

  Fly   523 IQQFAKQAHPPNNKPGDPNCDPRFYHNEWTWWQDEKASSSGT 564
            :.||.|.|.|....|.||..:||.....|..|..|::....|
  Rat   521 LSQFNKTAVPVRYPPKDPRSNPRLNGGVWGPWYKEESKKKKT 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	154/418 (37%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	153/412 (37%)
Arsj	NP_001041352.1	AslA	71..507	CDD:225661	169/501 (34%)
		4-S	74..507	CDD:293753	169/498 (34%)
		DUF4976	<493..>531	CDD:303608	17/39 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010