DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7408 and Gns

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_006241458.1	Gene:	Gns / 299825	RGDID:	1305877	Length:	544	Species:	Rattus norvegicus

Alignment Length:	595	Identity:	136/595 - (22%)
Similarity:	228/595 - (38%)	Gaps:	206/595 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLTGFVLCIALSNGIVATSDKPNIIIIMADDLGFDDVSFRGSNNFLTP--NIDAL-AYSGVILNN 75
            ||:|   |:    |:|..:.:||:::::.||   .|....|    :||  ...|| ...|:..::
  Rat    25 LLSG---CL----GLVGAARRPNVLLLLTDD---QDAELGG----MTPLKKTKALIGEKGMTFSS 75

  Fly    76 LYV-APMCTPSRAALLTGKYPINTGMQHYVIVN--------------DQPWGLPLNETTMAEIFR 125
            .|| :.:|.||||::||||||.|    |:|:.|              .:|:..|      |.:..
  Rat    76 AYVPSALCCPSRASILTGKYPHN----HHVVNNTLEGNCSSKSWQKIQEPYTFP------AILKL 130

  Fly   126 ENGYRTSLLGKWHLGLSQRNFTPTERGFDR-HLGYLGAYVDYYTQSYEQQNKGYNGHDFRDSLK- 188
            ..||:|...||:   |::.. .|...|.:. .||:      .|..:.|:.:|.||   :..|:.
  Rat   131 VCGYQTFFAGKY---LNEYG-APDAGGLEHVPLGW------SYWYALEKNSKYYN---YTLSING 182

  Fly   189 STHDHVGHYVTDLLTDAAVK---EIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQ--------A 242
            ....|..:|..|.|||....   :..|:  |::|:|.|::::..|||:.....|..        |
  Rat   183 KARRHGENYSVDYLTDVLANLSLDFLDY--KSNSEPFFMMISTPAPHSPWTAAPQYQKAFPNVIA 245

  Fly   243 PAEE---------------------VSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQ 286
            |..:                     .|..:::.:...|.:..::| :|..|..::..|.....|.
  Rat   246 PRNKNFNIHGTNKHWLIRQAKTPMTNSSIKFLDDAFRRRWQTLLS-VDDLVEKLVKRLDSTGELD 309

  Fly   287 NSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIGD 351
            |:.|.:.||||..|              ||.:.|                     :.|:|:|..|
  Rat   310 NTYIFYTSDNGYHT--------------GQFSLP---------------------IDKRQLYEFD 339

  Fly   352 L-LPTLAAAAGISPDPALHLDGLNLWSALKYGYESVEREIVHVID-----EDVAEPHLSYTRGKW 410
            : :|.|....||.|:                   ...:.:|..||     .|:|...|:.|:
  Rat   340 IKVPLLVRGPGIKPN-------------------QTSKMLVSNIDLGPTILDLAGYDLNKTQ--- 382

  Fly   411 KVISGTTNQGLY--DGWLGHRETSEVDPRAVEYEELVRNTSVWLQLQQVSFGE-RNISELRDQSR 472
              :.||:...:.  ||.|..|  |:|   .|||:                 || ||:::
  Rat   383 --MDGTSLLPILKGDGNLTWR--SDV---LVEYQ-----------------GEGRNVTD------ 417

  Fly   473 IECPDPATGVKPCLPLEGPCLFDIEAD---PCERS-----NL-YAEYQNSTIFLDLWS------R 522
            ..||..:.||..|.|   .|:.:...:   .|.|:     || |.|:.:..:|:::::      :
  Rat   418 PTCPSLSPGVSQCFP---DCVCEDAYNNTYACVRTLSSMWNLQYCEFDDQEVFVEVYNITADPDQ 479

  Fly   523 IQQFAKQAHP 532
            |...||...|
  Rat   480 ITNIAKSIDP 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	100/453 (22%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	99/447 (22%)
Gns	XP_006241458.1	G6S	38..487	CDD:293766	129/571 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351105
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740