Protein Alignment CG7408 and GALNS

DIOPT Version :9

• Sequence 1: NP_001163462.1
• Gene: CG7408 / 39991
• FlyBaseID: FBgn0036765
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: XP_011521284.1
• Gene: GALNS / 2588
• HGNCID: 4122
• Length: 581
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 144/591 - (24%)
• Similarity: 224/591 - (37%)
• Gaps: 151/591 - (25%)

  Fly    44 DLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYVA-PMCTPSRAALLTGKYPINTGM------- 100
            ::|:.|:...|..:..|||:|.:|..|::..|.|.| |:|:|||||||||:.||..|.
Human    46 EMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCSPSRAALLTGRLPIRNGFYTTNAHA 110

  Fly   101 QHYVIVNDQPWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHLG----YLG 161
            ::.....:...|:|.:|..:.|:.::.||.:.::|||||| .:..|.|.:.|||...|    :.|
Human   111 RNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLG-HRPQFHPLKHGFDEWFGSPNCHFG 174

  Fly   162 AY-------VDYYTQSYEQQNKGYNGHDFRDSLKSTHDHVGHYVTDLLTDAAVKEIEDHGSKNSS 219
            .|       :..| :.:|...:.|  .:|..:||:...::.........|...::...|
Human   175 PYDNKARPNIPVY-RDWEMVGRYY--EEFPINLKTGEANLTQIYLQEALDFIKRQARHH------ 230

  Fly   220 QPLFLLLNHLAPHAANDDDPMQAPAEEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEM 284
             |.||.....|.||     |:.|..      .::.......|...|..:|.|:|.:::.|....:
Human   231 -PFFLYWAVDATHA-----PVYASK------PFLGTSQRGRYGDAVREIDDSIGKILELLQDLHV 283

  Fly   285 LQNSIILFLSDNG-----GPTQGQHSTTASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWK 344
            ..|:.:.|.||||     .|.||     .||.|....|.:.:||.:|..|..|.......|.|..
Human   284 ADNTFVFFTSDNGAALISAPEQG-----GSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSH 343

  Fly   345 QQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTRGK 409
            |...|.||..|..|.||::|.....:|||||...|..|         .::|..:     .|.||.
Human   344 QLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQG---------RLMDRPI-----FYYRGD 394

  Fly   410 WKVISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRNTSVWLQLQQ-VSF--GERNIS-----E 466
             .:::.|..|.....|..                    |:.|...:| :.|  |: |:|     .
Human   395 -TLMAATLGQHKAHFWTW--------------------TNSWENFRQGIDFCPGQ-NVSGVTTHN 437

  Fly   467 LRDQSRIECPDPATGVKPCLPLEGPCLFDIEADPCER---SNLYAEYQNSTIFLDLWSRIQQFAK 528
            |.|.:::                 |.:|.:..||.||   |...||||.:.      |||....:
Human   438 LEDHTKL-----------------PLIFHLGRDPGERFPLSFASAEYQEAL------SRITSVVQ 479

  Fly   529 Q----------------------------AHPPNNKPGDPNCDPRFYHNEWTWWQDEKASSSGTI 565
            |                            ..|...:|..|..:.|.:|.  :..|..|...:..:
Human   480 QHQEALVPAQPQLNVCNWAVMAPTQSSTSVQPDKTRPCSPPVEKRPHHA--SIGQKHKHRRASKV 542

  Fly   566 GVMKVF 571
            .:..||
Human   543 SLKSVF 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	110/404 (27%)
		4-S	35..423	CDD:293753	110/402 (27%)
GALNS	XP_011521284.1	GALNS	46..500	CDD:293776	135/539 (25%)
		AslA	46..489	CDD:225661	135/528 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157188
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740