Protein Alignment CG7408 and SULF1

DIOPT Version :10

• Sequence 1: NP_649020.1
• Gene: CG7408 / 39991
• FlyBaseID: FBgn0036765
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001399757.1
• Gene: SULF1 / 23213
• HGNCID: 20391
• Length: 1122
• Species: Homo sapiens
• Alignment Length: 584
• Identity: 133/584 - (22%)
• Similarity: 219/584 - (37%)
• Gaps: 147/584 - (25%)

  Fly    34 KPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYV-APMCTPSRAALLTGKYPIN 97
            :||||:::.||   .||.. ||...:......:.:.|....|.:| .|||.|||:::|||||..|
Human    42 RPNIILVLTDD---QDVEL-GSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHN 102

  Fly    98 TGMQHYVIVNDQ-----PWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHL 157
                |.|..|::     .|.......|.|......||||:..||:   |::.|.:....|:...|
Human   103 ----HNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKY---LNEYNGSYIPPGWREWL 160

  Fly   158 GYLGAYVDYYTQSYEQQNKGYNGHDFRDSLKSTH--DHVGHYVTDLLTDAAVKEIEDHGSKNSSQ 220
            |.:            :.::.||....|:.:|..|  |:...|.|||:|:.::...:........:
Human   161 GLI------------KNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHR 213

  Fly   221 PLFLLLNHLAPHAANDDDPM------QAPAEEVSRFEYISN--------------KTHRYYAAMV 265
            |:.::::|.|||...|..|.      .|.......:.|..|              ..|..:..::
Human   214 PVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNIL 278

  Fly   266 SR--------LDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWE 322
            .|        :|.||..:.:.|.....|:|:.|::.:|:     |.|   ...:.|...|:.|::
Human   279 QRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADH-----GYH---IGQFGLVKGKSMPYD 335

  Fly   323 GALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVE 387
            ..:|....|.....|. ||:..|.:...||.||:...||:...|  .:||
Human   336 FDIRVPFFIRGPSVEP-GSIVPQIVLNIDLAPTILDIAGLDTPP--DVDG--------------- 382

  Fly   388 REIVHVIDEDVAEPHLSY-TRGKWKVISGTTNQGLYDGWLGHRETSEVDPRAV--EYEELVRNTS 449
            :.::.::|.:  :|...: |..|.|:            |   |:|..|:....  :.||..:|..
Human   383 KSVLKLLDPE--KPGNRFRTNKKAKI------------W---RDTFLVERGKFLRKKEESSKNIQ 430

  Fly   450 VWLQLQQVSFGERNISELRDQSRI-----------ECPDPATGVKPCLPLEGPCLFDIEADPCER 503
               |...:...|| :.||..|:|.           :|.:..:|.......:||.  |:.......
Human   431 ---QSNHLPKYER-VKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPS--DLLTVRQST 489

  Fly   504 SNLYAE---------------YQNSTIFLDLWSRIQQFAKQAHPPNNKPGDPNCDPRFYHNEWT 552
            .||||.               |:.        ||.|:.:::....|.  |.|...|||.|...|
Human   490 RNLYARGFHDKDKECSCRESGYRA--------SRSQRKSQRQFLRNQ--GTPKYKPRFVHTRQT 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_649020.1	4-S	35..423	CDD:293753	98/424 (23%)
SULF1	NP_001399757.1	G6S	42..384	CDD:293766	93/390 (24%)
		DUF3740	534..679	CDD:463628	5/10 (50%)
		ALP_like	<768..817	CDD:474031