DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7408 and sul-1

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_508560.1	Gene:	sul-1 / 180619	WormBaseID:	WBGene00006308	Length:	709	Species:	Caenorhabditis elegans

Alignment Length:	401	Identity:	99/401 - (24%)
Similarity:	159/401 - (39%)	Gaps:	108/401 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 NIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYV-APMCTPSRAALLTGKYPINTG 99
            |:|:|:.||   .|:.. ||.:|:......:...|....:.|| .|:|.|||:.:|||.|..|
Worm    36 NVILILTDD---QDIEL-GSMDFMPKTSQIMKERGTEFTSGYVTTPICCPSRSTILTGLYVHN-- 94

  Fly   100 MQHYVIVNDQ-----PWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHLGY 159
              |:|..|:|     .|.....:.::....:|.||||:                          |
Worm    95 --HHVHTNNQNCTGVEWRKVHEKKSIGVYLQEAGYRTA--------------------------Y 131

  Fly   160 LGAYVDYYTQSY-----------EQQNKGY----NGHDFRDSLKSTHDHVGHYVTDLLTDAAVKE 209
            ||.|::.|..||           .:.:|.|    |.:..|:...|.::.  .|.|||:|:.::|.
Worm   132 LGKYLNEYDGSYIPPGWDEWHAIVKNSKFYNYTMNSNGEREKFGSEYEK--DYFTDLVTNRSLKF 194

  Fly   210 IEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAPAEEVSRFEYISNKT----------------- 257
            |:.|....:.||..|::::.|||...|..|..|...|    ..||::|
Worm   195 IDKHIKIRAWQPFALIISYPAPHGPEDPAPQFAHMFE----NEISHRTGSWNFAPNPDKQWLLQR 255

  Fly   258 ---------------HRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTT 307
                           ||.....:..:|:.:..:.:.|.....|.|:..::.||:|... ||...
Worm   256 TGKMNDVHISFTDLLHRRRLQTLQSVDEGIERLFNLLRELNQLWNTYAIYTSDHGYHL-GQFGL- 318

  Fly   308 ASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIG-DLLPTLAAAAGISPDPALHLD 371
                 |:| ||.|:|..:|....:......|  :|...:|... |:.||:...||: |.|| .::
Worm   319 -----LKG-KNMPYEFDIRVPFFMRGPGIPR--NVTFNEIVTNVDIAPTMLHIAGV-PKPA-RMN 373

  Fly   372 GLNLWS--ALK 380
            |.:|..  |||
Worm   374 GRSLLELVALK 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	99/401 (25%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	99/401 (25%)
sul-1	NP_508560.1	G6S	34..376	CDD:293766	95/391 (24%)
		AslA	36..>381	CDD:225661	96/396 (24%)
		ALP_like	<605..654	CDD:304875
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810