DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7408 and Sulf1

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_008761708.1	Gene:	Sulf1 / 171396	RGDID:	708554	Length:	1117	Species:	Rattus norvegicus

Alignment Length:	583	Identity:	138/583 - (23%)
Similarity:	224/583 - (38%)	Gaps:	145/583 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYV-APMCTPSRAALLTGKYPIN 97
            :||||:::.||   .||.. ||...:......:.:.|....|.:| .|||.|||:::|||||..|
  Rat    42 RPNIILVLTDD---QDVEL-GSLQVMNKTRKIMEHGGATFTNAFVTTPMCCPSRSSMLTGKYVHN 102

  Fly    98 TGMQHYVIVNDQPWGLP----LNE-TTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHL 157
                |.|..|::....|    |:| .|.|......||||:..||:   |::.|.:....|:...|
  Rat   103 ----HNVYTNNENCSSPSWQALHEPRTFAVYLNNTGYRTAFFGKY---LNEYNGSYIPPGWREWL 160

  Fly   158 GYLGAYVDYYTQSYEQQNKGYNGHDFRDSLKSTH--DHVGHYVTDLLTDAAVKEIEDHGSKNSSQ 220
            |.:            :.::.||....|:.:|..|  |:...|.|||:|:.::...:........:
  Rat   161 GLI------------KNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHR 213

  Fly   221 PLFLLLNHLAPHAANDDDPM------QAPAEEVSRFEYISN--------------KTHRYYAAMV 265
            |:.::::|.|||...|..|.      .|.......:.|..|              ..|..:..::
  Rat   214 PVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNVL 278

  Fly   266 SR--------LDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWE 322
            .|        :|.||..:.:.|.....|.|:.|::.:|:     |.|   ...:.|...|:.|::
  Rat   279 QRKRLQTLMSVDDSVERLYNMLVETGELGNTYIIYTADH-----GYH---IGQFGLVKGKSMPYD 335

  Fly   323 GALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVE 387
            ..:|....|.....|. ||:..|.:...||.||:...||:  |....:||.::...|
  Rat   336 FDIRVPFFIRGPSIEP-GSIVPQIVLNIDLAPTILDIAGL--DTPSDVDGKSVLKLL-------- 389

  Fly   388 REIVHVIDEDVAEPHLSY-TRGKWKVISGTTNQGLYDGWLGHRETSEVDPRAV--EYEELVRNTS 449
                     |:.:|...: |..|.|:            |   |:|..|:....  :.||..:|..
  Rat   390 ---------DLEKPGNRFRTNKKAKI------------W---RDTFLVERGKFLRKKEESSKNIQ 430

  Fly   450 VWLQLQQVSFGERNISELRDQSRIE--CPDPATGVKPCLPLEGPCLFD----IEADPCE-RSNLY 507
               |...:...|| :.||..|:|.:  |..|....:        |:.|    :....|: .|:|.
  Rat   431 ---QSNHLPKYER-VKELCQQARYQTACEQPGQNWQ--------CIEDTSGKLRIHKCKGPSDLL 483

  Fly   508 AEYQNSTIFLDLWSR-IQQFAKQAH-------PPNNK----------PGDPNCDPRFYHNEWT 552
            ...||:.   :|:|| :|...|:.|       |..::          .|.|...|||.|...|
  Rat   484 TVRQNAR---NLYSRGLQDKDKECHCRESGYRPSRSQRKKERQFLRNQGTPKYKPRFVHTRQT 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	101/427 (24%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	101/424 (24%)
Sulf1	XP_008761708.1	G6S	42..384	CDD:293766	95/375 (25%)
		DUF3740	534..675	CDD:403667	5/10 (50%)
		ALP_like	<767..816	CDD:419962
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351097
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740