Protein Alignment CG7408 and Ids

DIOPT Version :10

• Sequence 1: NP_649020.1
• Gene: CG7408 / 39991
• FlyBaseID: FBgn0036765
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001388855.1
• Gene: Ids / 15931
• MGIID: 96417
• Length: 595
• Species: Mus musculus
• Alignment Length: 658
• Identity: 148/658 - (22%)
• Similarity: 225/658 - (34%)
• Gaps: 231/658 - (35%)

  Fly    13 SLLTGFVLCIALSNGIVATS--DKPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNN 75
            |||.| ..||||.:.....|  |..||::|:.|||. ..:...|.....:||||.||...|:..|
Mouse    16 SLLLG-SFCIALESAAQGNSATDALNILLIIVDDLR-PSLGCYGDKLVRSPNIDQLASHSVLFQN 78

  Fly    76 LYV-APMCTPSRAALLTGKYPINTGMQHYVIVNDQPWGLPL-NETTMAEIFRENGYRTSLLGK-W 137
            .:. ..:|.|||.:.|||:.|..|.:..:    :..|.:.. |.:|:.:.|:||||.|..:|| :
Mouse    79 AFAQQAVCAPSRVSFLTGRRPDTTRLYDF----NSYWRVHSGNFSTIPQYFKENGYVTMSVGKVF 139

  Fly   138 HLGLSQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQN----KGYNGH---------DFRDSLKS 189
            |.|:|..:        .....|..::..|:..|.:.:|    ||.:|.         |..|..:.
Mouse   140 HPGISSNH--------SDDYPYSWSFPPYHPSSEKYENTKTCKGQDGKLHANLLCPVDVADVPEG 196

  Fly   190 THDHVGHYVTD-LLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPH--------------------- 232
            |       :.| ..|:.|::.:|.  .|.|:.|.||.:.:..||
Mouse   197 T-------LPDKQSTEEAIRLLEK--MKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLA 252

  Fly   233 ---------------------------AANDDDP------------------------------- 239
                                       |.|...|
Mouse   253 PDPHVPDSLPPVAYNPWMDIREREDVQALNISVPYGPIPEDFQHRCSICSILILRQSSCESSWKE 317

  Fly   240 --------MQAPAEEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDN 296
                    .|.|:|.:..|  ...|..:.|.|.||.||..||.|:.||....:..|:||.|.||:
Mouse   318 HLLLLSRGFQLPSEVLCLF--AERKIRQSYFASVSYLDTQVGHVLSALDDLRLAHNTIIAFTSDH 380

  Fly   297 GGPTQGQHSTTA--SNY-------------------PLRGQKNSPWEGALRSSAAIWSTEFERLG 340
            |. ..|:|...|  ||:                   |..|||..|:.... ..|:.|..    .|
Mouse   381 GW-ALGEHGEWAKYSNFDVATRVPLMLYVPGRTAPLPAAGQKLFPYRDPF-DPASDWMD----AG 439

  Fly   341 SVWKQQIYIGDLLPTLAAAAGI-----SPDPALHL----DGLNLWSALKYGYESVEREIVHVIDE 396
            ...:..:.:..|.||||..||:     .|.|:.|:    :|.||...|:          :|.::|
Mouse   440 RHTEDLVELVSLFPTLAGLAGLPVPPRCPIPSFHVELCREGQNLQKHLQ----------LHDLEE 494

  Fly   397 DVAEPHL-----------SYTR----GKWKVISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVR 446
               ||.|           .|.|    .:|.....:.|.....|:         ..|.|:|
Mouse   495 ---EPDLFGNPRELIAYSQYPRPADFPQWNSDKPSLNDIKVMGY---------SIRTVDY----- 542

  Fly   447 NTSVWLQLQQVSFGERNISELRDQSRIECPDPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQ 511
            ..:||     |.|                 ||:..:.....:....|:.:::||.:..|:|.:.|
Mouse   543 RYTVW-----VGF-----------------DPSEFLANFSDIHAGELYFVDSDPLQDHNVYNDSQ 585

  Fly   512 NSTIFLDL 519
            :..:...|
Mouse   586 HGGLLHSL 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_649020.1	4-S	35..423	CDD:293753	121/536 (23%)
Ids	NP_001388855.1	iduronate-2-sulfatase	40..586	CDD:293754	136/624 (22%)