DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7408 and arsb

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_021324609.1	Gene:	arsb / 100538007	ZFINID:	ZDB-GENE-111123-2	Length:	502	Species:	Danio rerio

Alignment Length:	564	Identity:	179/564 - (31%)
Similarity:	264/564 - (46%)	Gaps:	118/564 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 VLCIALSNGIVATSDKPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYVAPMCT 83
            :||:.|.   ..::..|::::|:|||||::||.|.|| ...||::|.||..||.|:|.||.|:||
Zfish    10 LLCVVLE---CVSARPPHVVLILADDLGWNDVGFHGS-EIKTPHLDRLAAQGVRLDNYYVQPLCT 70

  Fly    84 PSRAALLTGKYPINTGMQHYVIVNDQPWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTP 148
            |||..|:||:|.|.||:||.:|...||:.:||:|..:.::.||.||.|.::||||||:.|::..|
Zfish    71 PSRNQLMTGRYQIRTGLQHQIIWPCQPYCVPLDEKLLPQVLRERGYHTHMVGKWHLGMFQKDCLP 135

  Fly   149 TERGFDRHLGYLGAYVDYYTQS----YEQQNKGYNGHDFRDSLKSTHDHVGHYVTDLLTDAAVKE 209
            |.|||....|||....||||..    ....|......|.||......::.|.|.|:|||:.|...
Zfish   136 THRGFQSFFGYLTGSEDYYTHKRCSPIAPLNVTRCALDLRDGDAVALNYSGRYSTELLTERATHI 200

  Fly   210 IEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAPAEEVSRFEYISNKTHRYYAAMVSRLDKSVGS 274
            |..|   ...|||||.:...|.||     |:|.|...::.:.:|.:...|.||.|||.:|::||:
Zfish   201 ITQH---TPDQPLFLYVALQAVHA-----PLQVPDHYIAPYSFIQDPHRRRYAGMVSAMDEAVGN 257

  Fly   275 VIDALARQEMLQNSIILFLSDNGGPT-QGQHSTTASNYPLRGQKNSPWEGALRSSAAIWSTEFER 338
            :...|....:..|::::|.:||||.| .|     .:|:||||:|.:.|||.:|..|.:.....|:
Zfish   258 ITHTLQETGLWDNTVLIFSTDNGGQTLYG-----GNNWPLRGRKWTLWEGGVRGVAFVSGPLIEK 317

  Fly   339 LGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVEREIVHVID-------- 395
            .|:|.::.|:|.|.|||:|..||.|.:....|||.::|.::..|..|...|::|.||
Zfish   318 PGAVNRELIHISDWLPTIAGLAGASTNGTKPLDGFDVWQSISAGVASPRVELLHNIDPLYEDSSP 382

  Fly   396 ------------------------EDVAEP-----HLSYTRGKWKVISGTTNQGLYDGWLGHRET 431
                                    .||:..     |.:.....||:::|      |.|
Zfish   383 CPGGEGVFLEDSLHSSSSSSSSSSSDVSAQFNISIHAAIRHKNWKLLTG------YPG------- 434

  Fly   432 SEVDPRAVEYEELVRNTSVWLQLQQVSFGERNISELRDQSRIECPDPATGVKP---CLPLEGPCL 493
                            ..:|:                         |..|.:|   ..||:...|
Zfish   435 ----------------CPLWI-------------------------PPPGGRPVNASEPLKQVML 458

  Fly   494 FDIEADPCERSNLYAEYQNSTIFLDLWSRIQQFAKQAHPPNNKP 537
            ||:|.||.||  |...:|...:...|..|:|....||.|.:..|
Zfish   459 FDVEKDPEER--LEVSHQRPEVVSFLLRRLQLCQNQAQPIHFPP 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	152/435 (35%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	151/429 (35%)
arsb	XP_021324609.1	4-S	23..472	CDD:293753	168/518 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592920
Domainoid	1	1.000	294	0.414	Domainoid score	I1467
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2236
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	1	1.000	-	-		FOG0000852
OrthoInspector	1	1.000	-	-		mtm6503
orthoMCL	1	0.900	-	-		OOG6_100690
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X499
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.800