DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7408 and arsi

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_002940132.1	Gene:	arsi / 100487216	XenbaseID:	XB-GENE-6046190	Length:	575	Species:	Xenopus tropicalis

Alignment Length:	598	Identity:	190/598 - (31%)
Similarity:	273/598 - (45%)	Gaps:	101/598 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ATSLLTGFVLCIALSNGIVA-----------------------TSDKPNIIIIMADDLGFDDVSF 52
            |...||||.|...||.|.::                       .|..|:||.|:.||.||.||.:
Frog     2 AVHALTGFSLVSLLSFGYMSWDWVKPAVLGDSPGDEPAKLQGTPSRPPHIIFILTDDQGFHDVGY 66

  Fly    53 RGSNNFLTPNIDALAYSGVILNNLYVAPMCTPSRAALLTGKYPINTGMQHYVIVNDQPWGLPLNE 117
            .|| :..||.:|.||..||.|.|.|:.|:|||||:.|:||:|.|:||:||.:|...||..|||::
Frog    67 HGS-DIQTPTLDRLAAEGVKLENYYIQPICTPSRSQLITGRYQIHTGLQHSIIRPRQPNCLPLHQ 130

  Fly   118 TTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQ-QNKGYNGH 181
            .|:.:..:|.||.|.::||||||..::...||.||||..||.|...||||  ||:. ...|..|.
Frog   131 VTLPQKLQEAGYSTHMVGKWHLGFYKKECLPTRRGFDTFLGSLTGNVDYY--SYDNCDGPGVCGF 193

  Fly   182 DFRDSLKSTHDHVGHYVTDLLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAPAEE 246
            |..:......|..|.|.| ||....|.:|  ..|.|..||:|:.:...|.|.     |:|:|.|.
Frog   194 DLHEGENVAWDQAGKYST-LLYAQRVNQI--LASHNPQQPIFIYVAFQAVHT-----PLQSPREY 250

  Fly   247 VSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTASNY 311
            :..:..:.|...|.|||||:.:|.:|.::..||.:.....||:|:|.|||||.|    .:..||:
Frog   251 IYPYRGMGNVARRKYAAMVTCMDAAVKNITRALKKYGYYSNSVIVFSSDNGGQT----FSGGSNW 311

  Fly   312 PLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLW 376
            ||||:|.:.|||.:|....:.|...::.....:..::|.|..|||...||.:...|..|||.::|
Frog   312 PLRGRKGTYWEGGVRGLGFVHSPLIKKKRRTSRALMHITDWYPTLVKLAGGNISSAEGLDGYDVW 376

  Fly   377 SALKYGYESVEREIVHVIDE--DVAEP-HLSYTRGKW-------------KVISGTTNQGLYDGW 425
            .|:..|.||...||:|.||.  ::|:. .|...:|.|             |:::|...   |..|
Frog   377 GAISEGKESPRTEILHNIDPLYNLAKSGSLEEGQGVWNTAVQASIRVKDFKLLTGDPG---YSDW 438

  Fly   426 LGHRETSEVDPRAVEYEELVRNTSVWLQLQQVSFGERNISELRDQSRIECPDPATGVKPCLPLEG 490
                    :.|     :.|......|..|::.:.|.|                          :.
Frog   439 --------IPP-----QTLTNFPGSWWNLERHTDGAR--------------------------KS 464

  Fly   491 PCLFDIEADPCERSNLYAEYQNSTIFLDLWSRIQQFAKQAHPPNNKPGDPNCDPRFYHNEWTWW- 554
            ..||:|.|||.||.:|.:  ....:..:|..|:..:.:.|.|......||..:|......|..|
Frog   465 LWLFNITADPFERHDLSS--SKPEVVKELLIRLGYYNRTAIPVRYPAEDPRGNPELNGGAWGPWA 527

  Fly   555 -QDEKASSSGTIG 566
             :|:.......||
Frog   528 SEDDDDEEENWIG 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	153/410 (37%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	151/404 (37%)
arsi	XP_002940132.1	4-S	49..481	CDD:293753	167/488 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8784
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H44428
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2217
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	1	1.000	-	-		FOG0000852
OrthoInspector	1	1.000	-	-		mtm9380
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X499
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.970