DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7408 and galns

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_002933701.2	Gene:	galns / 100485376	XenbaseID:	XB-GENE-1000591	Length:	520	Species:	Xenopus tropicalis

Alignment Length:	575	Identity:	153/575 - (26%)
Similarity:	237/575 - (41%)	Gaps:	138/575 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SLLTGFVLCIALSNGIVATSDKPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLY 77
            :|..||:..:.:..|:..|  :|||::::.||:|:.|:...|..:..|||:|.:|..|::..|.|
Frog     8 ALALGFLNPVLVLGGMNGT--RPNILLLLMDDMGWGDLGVFGEPSRETPNLDKMASEGMLFPNFY 70

  Fly    78 VA-PMCTPSRAALLTGKYPINTGMQHYVIVNDQP----------WGLPLNETTMAEIFRENGYRT 131
            .| |:|:|||||||||:.||..|   :...|...          .|:|.:|....|:.::.||..
Frog    71 TANPLCSPSRAALLTGRLPIRNG---FYTTNSHARNAYTPQEIMGGIPDSEVLFPELLKKAGYVN 132

  Fly   132 SLLGKWHLGLSQRNFTPTERGFDRHLG----YLGAYVDYYTQSYEQQNKGY-NGHDFRDSLKSTH 191
            .::|||||| .:.::.|..||||...|    :.|.|          .||.. |...:||     .
Frog   133 KIIGKWHLG-HRPSYHPLRRGFDEWFGSPNCHFGPY----------DNKQRPNIPVYRD-----W 181

  Fly   192 DHVGHYVTDL----------LTDAAVKEIEDHGSKNS--SQPLFLLLNHLAPHAANDDDPMQAPA 244
            |.||.|..|.          ||...::|..:..::.:  .||.||..:..|.||     |:.|
Frog   182 DMVGRYYEDFNIDHKTGESNLTQIYLQEALEFINRQAGDQQPFFLYWSIDATHA-----PVYA-- 239

  Fly   245 EEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDNG-----GPTQGQH 304
               || .::.......|...|..:|.|:|.::..|.::::::::.:.|.||||     .|.||
Frog   240 ---SR-PFLGTSRRGLYGDAVREIDFSIGKILGLLNQKDIIKDTFVFFTSDNGAALISAPMQG-- 298

  Fly   305 STTASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALH 369
               .||.|....|.:.:||.:|.....|.......|.|..|...|.||..|..:.||:.......
Frog   299 ---GSNGPFLCGKQTTFEGGMRVPGIAWWPGHVAPGQVSYQLGSIMDLFTTSLSLAGVEIPKDRA 360

  Fly   370 LDGLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTRGKWKVISGTTNQGLYDGWLGHRETSEV 434
            :||::|...:   .||.|.|          .|...|...:...:....::..|..|
Frog   361 IDGIDLSPVI---LESEETE----------RPIFYYRGNELMAVRLGQHKAHYWTW--------- 403

  Fly   435 DPRAVEYEELVRNTSVWLQLQQ-VSFGERNISELRDQSRIECP-DPATGVKPCLPLE---GPCLF 494
                         ::.|.:|.| ::|               || ...|||...:.:|   .|.||
Frog   404 -------------SNSWEELSQGINF---------------CPGQNITGVTTHVQVEHSINPLLF 440

  Fly   495 DIEADPCER---SNLYAEYQNSTIFLDLWSRIQQFAKQAHPPNNKPGDPN---CD 543
            .:..||.|:   |.|..||:.:.      |||....:| |..:..||:|.   ||
Frog   441 HLGRDPGEKYSISVLSTEYEAAL------SRISPVVQQ-HRNSMVPGEPQLNVCD 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	118/426 (28%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	116/420 (28%)
galns	XP_002933701.2	GALNS	27..492	CDD:293776	148/554 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910