DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7408 and arsk

DIOPT Version :9

Sequence 1:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_017946283.2	Gene:	arsk / 100485065	XenbaseID:	XB-GENE-1000369	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	580	Identity:	119/580 - (20%)
Similarity:	195/580 - (33%)	Gaps:	200/580 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 CIALS---------------NGIVATSDKPNIIIIMADDLGFDDVSFRGSNNFL-------TPNI 63
            |||:|               ..:...|.|.|::::|:|       :|.|....|       .|.|
Frog     5 CIAVSLFLFSAVPEDIPVRALSLSPNSPKHNVVMVMSD-------AFDGRLTLLPEKSLVSLPYI 62

  Fly    64 DALAYSGVILNNLYV-APMCTPSRAALLTGKYP-INTGMQHYVIVNDQPWGLPLNETTMAEIFRE 126
            :.:...|.:..|.|. :|:|.|||||:.:|.:| :.....:|..:|.:       ..|..:...:
Frog    63 NFMKQHGALFLNAYTNSPICCPSRAAMWSGLFPHLTESWNNYKCLNSE-------YPTWMDKVEK 120

  Fly   127 NGYRTSLLGKWHLGLSQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQNKGYNGHDFRDSLKSTH 191
            |||.|..|||........:.:.....:.|.:.:|                      .|...:...
Frog   121 NGYVTQRLGKQDYTSGSHSLSNRVEAWTRDVPFL----------------------LRQEGRPCA 163

  Fly   192 DHVGHYV-TDLLT------DAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDD----------- 238
            :..|:.. |.::|      |.|...|: ..::|||||.||.|....||....::
Frog   164 NLTGNKTQTRVMTQDWKNADTAAGWIQ-KAAQNSSQPFFLYLGLNLPHPYPSENMGENFGSSTFL 227

  Fly   239 ----------------PMQAPAEEVSRFEYISNKTH----------------RYYAAMVSRLDKS 271
                            |...|.:.:...:|.|:.|.                .|| ||.:..|..
Frog   228 TSSYWLQKVSYKNVTVPEWKPLQSMHPVDYYSSYTKNCTAPFTDQEIRDIRANYY-AMCAEADGL 291

  Fly   272 VGSVIDALARQEMLQNSIILFLSDNG--------------------------GP--TQGQHSTTA 308
            :|.:|.||....:|..:.::|.||:|                          ||  :.||..:|.
Frog   292 LGEIISALNDTGLLSRTYVVFTSDHGELAMEHRQFYKMSMYEGSSHVPLLIMGPGISPGQQISTI 356

  Fly   309 SN----YP------------------------LRGQKNSP--------WE-GALRSSAAIWSTEF 336
            .:    ||                        .|.:||.|        |. .....|.|..||..
Frog   357 VSLVDLYPTMLEIAGVQIPQNISGFSLMPLLSARSEKNVPSCTNAHPNWALSEFHGSDANASTYM 421

  Fly   337 ERLGSVWKQQIYI-GD-LLPTLAAAAGISPDPALHLDGL-NLWSALKYGYESVEREIVHVID--E 396
            .| .:.||...|. || ::|.|   ..:|.||    |.| |:.:.:....:.:::::..:||  :
Frog   422 LR-DNYWKYIAYADGDSVIPQL---FDLSSDP----DELRNVAAQVPEKVQEMDKKLRSIIDYAK 478

  Fly   397 DVAEPHLSYTRGK---WKVISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRNTSVWLQ 453
            ..|..|: |.:.:   ||...|.....:......|   |:.:.|...||..:..   ||:
Frog   479 VSASVHV-YNKQQFALWKASIGANYTNVISNLRWH---SDWNTRPNTYEMAIEK---WLK 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	108/525 (21%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	106/519 (20%)
arsk	XP_017946283.2	ARSK	35..450	CDD:293781	95/460 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910