Protein Alignment CG5535 and SLC7A7

DIOPT Version :10

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_003973.3
• Gene: SLC7A7 / 9056
• HGNCID: 11065
• Length: 511
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 118/528 - (22%)
• Similarity: 214/528 - (40%)
• Gaps: 118/528 - (22%)

  Fly    27 PLEDS-----NESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYA--GPAVVVSFLIAAIA 84
            ||.|.     .:.||.|.:|..:...|.:|:.:|.|::|....|....|  |.::|: :.:..:.
Human    19 PLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLF 82

  Fly    85 SIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWN--LILEYAIGSASVVKGLSTYLDQL 147
            |:|..|||||.|..:.|:|::|.|.....|.|:||:..|.  ||:| ....|.:....:.|:.|
Human    83 SVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIE-PTSQAIIAITFANYMVQ- 145

  Fly   148 CGNPMSSFLGTHMPLNIEGMGAYPDLFA-FVVTILFSLAI--------AVGAKESTRVNNVFTML 203
                         ||       :|..|| :..:.|.:.|.        ....|..|.|.::||..
Human   146 -------------PL-------FPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYA 190

  Fly   204 NLGVVLFVIIAGLFKV---SSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCI 265
            .:..::.||:||:.::   :|:::        |...:|.  .:.|..|........:.:.|:|.:
Human   191 KVLALIAVIVAGIVRLGQGASTHF--------ENSFEGS--SFAVGDIALALYSALFSYSGWDTL 245

  Fly   266 ATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPL----------PHVF 320
            ....||.|||::::|.::.:|:.::.:.|     :||.:..|...|.:..|          ..:|
Human   246 NYVTEEIKNPERNLPLSIGISMPIVTIIY-----ILTNVAYYTVLDMRDILASDAVAVTFADQIF 305

  Fly   321 RINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMIT 385
            .|..| :....|::....||.:|::.|    .|:.|..|.:|.|...:..|..:..||....:..
Human   306 GIFNW-IIPLSVALSCFGGLNASIVAA----SRLFFVGSREGHLPDAICMIHVERFTPVPSLLFN 365

  Fly   386 GMLTGILAAVFNLSQLVNMMSIG--TLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDR 448
            |::..|...|.::.||:|..|..  ..:..|:|..  |.||::                  |.||
Human   366 GIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQ--LYLRWK------------------EPDR 410

  Fly   449 PCALWRRIFNLNGQTVPTKQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFDGIKLVLGT 513
            |..|                  ::..:...:|.| |.:|...:..:.:   .:.|..||.:.|..
Human   411 PRPL------------------KLSVFFPIVFCL-CTIFLVAVPLYSD---TINSLIGIAIALSG 453

  Fly   514 IPLAVLLL 521
            :|...|::
Human   454 LPFYFLII 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	118/528 (22%)
SLC7A7	NP_003973.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		3/8 (38%)
		2A0308	20..493	CDD:273332	117/527 (22%)