DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5535 and TAT2

DIOPT Version :9

Sequence 1:NP_649019.2 Gene:CG5535 / 39990 FlyBaseID:FBgn0036764 Length:630 Species:Drosophila melanogaster
Sequence 2:NP_014622.1 Gene:TAT2 / 854139 SGDID:S000005380 Length:592 Species:Saccharomyces cerevisiae


Alignment Length:529 Identity:111/529 - (20%)
Similarity:210/529 - (39%) Gaps:116/529 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 KKPLEDS-NESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGP-AVVVSFLIAA--IAS 85
            |.||:.| :.|.|.:.|....|..:.||.::|.|::|.:|:...: .|| .||:.:.||.  |..
Yeast    66 KSPLDGSFDTSNLKRTLKPRHLIMIAIGGSIGTGLFVGSGKAIAE-GGPLGVVIGWAIAGSQIIG 129

  Fly    86 IFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEY-------AIGSASVVKGLSTY 143
            ...||  .|...|.|..|:...|....:...|:|::....:|::       .|.:|..|:..::.
Yeast   130 TIHGL--GEITVRFPVVGAFANYGTRFLDPSISFVVSTIYVLQWFFVLPLEIIAAAMTVQYWNSS 192

  Fly   144 LDQLCGNPMSSFLGTHMPLNIEGMGAYPDL-FAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGV 207
            :|.:..  ::.|....:.:|:.|:..:.:. ||| .||                 ...|:....:
Yeast   193 IDPVIW--VAIFYAVIVSINLFGVRGFGEAEFAF-STI-----------------KAITVCGFII 237

  Fly   208 VLFVIIAG-----LFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFY--GFIGFDCI 265
            :..|:|.|     .| :.:..|.           |.|.:..|..|::....|..|  |.|...|:
Yeast   238 LCVVLICGGGPDHEF-IGAKYWH-----------DPGCLANGFPGVLSVLVVASYSLGGIEMTCL 290

  Fly   266 ATAGEEAKNPKKSIPFAVIVSLAMIF---LAYFGVS-TVLTMMLPYFEQD-------EKAPLPHV 319
            | :||   ...|.:|.|:    ..:|   |.:|.:| |::..::||..|:       :.:|....
Yeast   291 A-SGE---TDPKGLPSAI----KQVFWRILFFFLISLTLVGFLVPYTNQNLLGGSSVDNSPFVIA 347

  Fly   320 FRINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMI 384
            .:::.......:|:...:..:.|.....:|...|.:.:|::.||:..:.|.| ::...|..|.| 
Yeast   348 IKLHHIKALPSIVNAVILISVLSVGNSCIFASSRTLCSMAHQGLIPWWFGYI-DRAGRPLVGIM- 410

  Fly   385 TGMLTGILAAVF---NLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQ 446
            ...|.|:||.:.   ::|::.|.     |:|.:.:|:|::.|...:...| .|:....:...|::
Yeast   411 ANSLFGLLAFLVKSGSMSEVFNW-----LMAIAGLATCIVWLSINLSHIR-FRLAMKAQGKSLDE 469

  Fly   447 -------------------------DRPCALWRRIFNLNGQTVPTKQTSRIV--TYSVTLFSLWC 484
                                     ...|:||    .:.|.| ..|:.::|.  .|...|..|:.
Yeast   470 LEFVSAVGIWGSAYSALINCLILIAQFYCSLW----PIGGWT-SGKERAKIFFQNYLCALIMLFI 529

  Fly   485 MVFSQILTK 493
            .:..:|..|
Yeast   530 FIVHKIYYK 538

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5535NP_649019.2 2A0303 20..585 CDD:273330 111/529 (21%)
AA_permease_C 535..585 CDD:290617
TAT2NP_014622.1 LysP 52..591 CDD:223903 111/529 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1286
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 90 1.000 Inparanoid score I1545
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53617
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.960

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