DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and AGP1

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_009905.3	Gene:	AGP1 / 850333	SGDID:	S000000530	Length:	633	Species:	Saccharomyces cerevisiae

Alignment Length:	497	Identity:	96/497 - (19%)
Similarity:	173/497 - (34%)	Gaps:	130/497 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VTNAFRVLTRKKPLEDSNES-------------KLAKVLSAFDLTALGIGSTLGVGVYVLAGEVS 66
            :|:|....:|:....:.|||             .|.|.:....:..:.:|:.:|.|:.|..| .:
Yeast    82 LTSAISPSSRQAQELEKNESSDNIGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLVGNG-TA 145

  Fly    67 KQYAGPA-VVVSFLIAAIASIFAGLCYAEFGARVPKAGS-AYIYSYVT----------IGEFIAF 119
            ..:|||| :::.:      :|...:.|....|    .|. |.:||.:|          :.:...|
Yeast   146 LVHAGPAGLLIGY------AIMGSILYCIIQA----CGEMALVYSNLTGGYNAYPSFLVDDGFGF 200

  Fly   120 LIGWNLILEYAIGSASVVKGLSTYLDQLCGNPMSSFLGTHMPLNIEGMGAYPDLFAFVVTILFSL 184
            .:.|...|::                 ||..|: ..:...|.:........||:|..:..:|...
Yeast   201 AVAWVYCLQW-----------------LCVCPL-ELVTASMTIKYWTTSVNPDVFVIIFYVLVIT 247

  Fly   185 AIAVGAKESTRVNNVFTMLNLGVVL-FVIIAGLFKVSSSNWSIPKSQVPEGYGDGGFM------- 241
            ....||:........|....:.::. |.|:..:..|.             |.|:.||:
Yeast   248 INIFGARGYAEAEFFFNCCKILMMTGFFILGIIIDVG-------------GAGNDGFIGGKYWHD 299

  Fly   242 PYGVSG-----IIKGAAVCF----YGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGV 297
            |...:|     ..||.|...    :.|.|.:.||....|..||:|:||.|....:..|...:...
Yeast   300 PGAFNGKHAIDRFKGVAATLVTAAFAFGGSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLAT 364

  Fly   298 STVLTMMLPYFEQDE---------KAPLPHVFRI--NGWHVAEYVVSIGAMFGLCSSMMGAMFPL 351
            ..:|..::|| ..|:         ||. |:|..:  :|..|..:.::...:..:.|....:.:..
Yeast   365 IILLGFLVPY-NSDQLLGSTGGGTKAS-PYVIAVASHGVRVVPHFINAVILLSVLSMANSSFYSS 427

  Fly   352 PRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGI---------------LAAVFNLSQL 401
            .|:...:|..|...|....| ::...|.....::.:...|               |.|:..||||
Yeast   428 ARLFLTLSEQGYAPKVFSYI-DRAGRPLIAMGVSALFAVIAFCAASPKEEQVFTWLLAISGLSQL 491

  Fly   402 VNMMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANGRATG 443
                       ::..|.|:..||:    ||..::  .||:.|
Yeast   492 -----------FTWTAICLSHLRF----RRAMKV--QGRSLG 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	94/492 (19%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
AGP1	NP_009905.3	2A0310	117..597	CDD:273334	89/462 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345725
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I1545
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	6	5.800