DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5535 and CAT9

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_563754.1	Gene:	CAT9 / 837104	AraportID:	AT1G05940	Length:	569	Species:	Arabidopsis thaliana

Alignment Length:	582	Identity:	175/582 - (30%)
Similarity:	278/582 - (47%)	Gaps:	93/582 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LEDSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLIAAIASIFAGLCY 92
            :..::...|.:.|..|||..||:|:::|.||:|:.|.|::. |||.|.:|||:|..:.:...|||
plant    40 VRSTSGDSLVRRLGLFDLILLGVGASIGAGVFVVTGTVARD-AGPGVTISFLLAGASCVLNALCY 103

  Fly    93 AEFGARVPK-AGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTY-------LDQLCG 149
            ||..:|.|. .|.||:|||....|..|||:...|:|:|.||:||:.:.|::|       ...|.|
plant   104 AELSSRFPAVVGGAYMYSYSAFNEITAFLVFVQLMLDYHIGAASISRSLASYAVALLELFPALKG 168

  Fly   150 N-PM-----SSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVV 208
            : |:     ...||..:.|||         .|.::..|.:|.:..|.:||:.||:|.|...:.:|
plant   169 SIPLWMGSGKELLGGLLSLNI---------LAPILLALLTLVLCQGVRESSAVNSVMTATKVVIV 224

  Fly   209 LFVIIAGLFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGEEAK 273
            |.||.||.|::..:|||             .|.|.|...::.||.|.|:.::|||.:|.:.||:|
plant   225 LVVICAGAFEIDVANWS-------------PFAPNGFKAVLTGATVVFFSYVGFDAVANSAEESK 276

  Fly   274 NPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVAEYVVSIGAMF 338
            ||::.:|..::.||.:....|.||..|||.|:|:....|.|||...|...|......::||||:.
plant   277 NPQRDLPIGIMGSLLVCISLYIGVCLVLTGMVPFSLLSEDAPLAEAFSSKGMKFVSILISIGAVA 341

  Fly   339 GLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQLVN 403
            ||.::::..::...|:...:..||||......|.....||....:..|::.|:||.:||:..|.:
plant   342 GLTTTLLVGLYVQSRLYLGLGRDGLLPSIFSRIHPTLHTPLHSQIWCGIVAGVLAGIFNVHSLSH 406

  Fly   404 MMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDRPCALWRRIFNLNGQTVPTKQ 468
            ::|:|||..||:||:||:.||......|||            .:|..:.|:.
plant   407 ILSVGTLTGYSVVAACVVALRLNDKKDRES------------SNRWTSSWQE------------- 446

  Fly   469 TSRIVTYSVTLFSLWCMVF-SQILTKFEEDLANVTSFDGIKLVLGTI---------PLAVLLLVI 523
                  ..:.|..:.|..| :.:..:|...:..:....|:.:|...:         ||.
plant   447 ------GVICLVIIACSGFGAGVFYRFSASVIFILLSVGVAVVASAVLHYRQAYALPLG------ 499

  Fly   524 SRQPTSGVKLSFKVPLVPWLPGISILINIYLMIKLDILTWIRFSIWIAIGLAIFLAYGIRHS 585
                 ||    |..|.||.:|.:.|..||:|..:|....||||.:...:..|::..||..|:
plant   500 -----SG----FSCPGVPIVPSVCIFFNIFLFAQLHYEAWIRFVVVSVLATAVYALYGQYHA 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	174/580 (30%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617	17/49 (35%)
CAT9	NP_563754.1	2A0303	42..552	CDD:273330	174/578 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D439017at2759
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.790