DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and Slc7a7

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_112631.1	Gene:	Slc7a7 / 83509	RGDID:	619902	Length:	512	Species:	Rattus norvegicus

Alignment Length:	514	Identity:	117/514 - (22%)
Similarity:	212/514 - (41%)	Gaps:	103/514 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYA--GPAVVVSFLIAAIASIFAGLCYA 93
            :.:.||.|.:|..:...|.:|:.:|.|::|....|....|  |.::|: :.:..|.|:|..||||
  Rat    31 AEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLMYSASFGLSLVI-WAVGGIFSVFGALCYA 94

  Fly    94 EFGARVPKAGSAYIYSYVTIGEFIAFLIGWN--LILEYAIGSASVVKGLSTYLDQ----LCGNPM 152
            |.|..:.|:|::|.|.....|.|:||:..|.  ||:| ....|.:....:.|:.|    .||.|.
  Rat    95 ELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIE-PTSQAVIAITFANYMVQPLFPSCGAPY 158

  Fly   153 SSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFVIIAGLF 217
                            |...|.|.....|.:.......|..|.|.::||...:..::.|||||:.
  Rat   159 ----------------AAGRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIIAGIV 207

  Fly   218 KV---SSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGEEAKNPKKSI 279
            ::   :::|:        |...:|.....|...:...:|:  :.:.|:|.:....||.:||::::
  Rat   208 RLGQGATTNF--------EDSFEGSSFAMGDIALALYSAL--FSYSGWDTLNYVTEEIRNPERNL 262

  Fly   280 PFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPL----------PHVFRINGWHVAEYVVSI 334
            |.::.:|:.::.:.|     :||.:..|...|.|..|          ..:|.|..|.: ...|::
  Rat   263 PLSIGISMPIVTIIY-----LLTNVAYYSVLDIKDILASDAVAVTFADQIFGIFNWTI-PLAVAL 321

  Fly   335 GAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLS 399
            ....||.:|::.|    .|::|..|.:|.|...:..|..:..||....:..|:|..:...|.::.
  Rat   322 SCFGGLNASIVAA----SRLLFVGSREGHLPDAICMIHVERFTPVPSLLFNGILALVYLCVEDIF 382

  Fly   400 QLVNMMSIG--TLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDRPCALWRRIFNLNGQ 462
            ||:|..|..  ..:..|:|..  |.||::                  |.|||..|
  Rat   383 QLINYYSFSYWFFVGLSIVGQ--LYLRWK------------------EPDRPRPL---------- 417

  Fly   463 TVPTKQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFDGIKLVLGTIPLAVLLL 521
                    ::..:...:|.| |.:|...:..:.:   .:.|..||.:.|..:|...|::
  Rat   418 --------KLSLFFPIVFCL-CTIFLVAVPLYSD---TINSLIGIGIALSGLPFYFLII 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	117/514 (23%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
Slc7a7	NP_112631.1	2A0308	24..496	CDD:273332	117/514 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351182
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850