DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5535 and CAT4

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001154586.1	Gene:	CAT4 / 821176	AraportID:	AT3G03720	Length:	600	Species:	Arabidopsis thaliana

Alignment Length:	613	Identity:	201/613 - (32%)
Similarity:	334/613 - (54%)	Gaps:	69/613 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LTRKKP------LEDSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLI 80
            |.|:|.      :::....:|||.|||.||.|:|:|:|:|.|||:|.|.|::::.|||:.|||.|
plant     4 LVRRKQVDSVHLIKNDGPHQLAKKLSAVDLVAIGVGTTIGAGVYILVGTVAREHTGPALAVSFFI 68

  Fly    81 AAIASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLD 145
            |.:|:..:..||||..:|.|.|||||.|:|:.:||.||:|:||.|:|:|.||.:::.:|::..|
plant    69 AGVAAALSACCYAELASRCPSAGSAYHYAYICLGEGIAWLVGWALVLDYTIGGSAIARGITPNL- 132

  Fly   146 QLCGNPMSSFLG--THMPL-----NIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTML 203
                   :||.|  .::|:     .|.|:|...|..|.::.::.::.:..|.|||:.|..:.|.:
plant   133 -------ASFFGGLDNLPVFLARQTIPGVGIVVDPCAALLIMIVTILLCFGIKESSTVQAIVTSV 190

  Fly   204 NLGVVLFVIIAGLFKVSSSNWSIPKSQVPEGYG-DGGFMPYGVSGIIKGAAVCFYGFIGFDCIAT 267
            |:..::|:|:.|.:....:.|        .||. ..|:.|:|::||:.|:||.|:.:||||.:.:
plant   191 NVCTLVFIIVVGGYLACKTGW--------VGYDLPSGYFPFGLNGILAGSAVVFFSYIGFDTVTS 247

  Fly   268 AGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVAEYVV 332
            ..||.|||::.:|..:.::|.:..:.|..:|.|:..::||:..:...|:...|..:|...|.|::
plant   248 TAEEVKNPQRDLPLGIGIALLICCILYMLLSVVIVGLVPYYSLNPDTPISSAFGDSGMQWAAYIL 312

  Fly   333 SIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFN 397
            :.||:..||:|::|::...|||..||:.||||..|..:||.:.:.|.|.|:..|:|...||...:
plant   313 TTGAITALCASLLGSLLAQPRIFMAMARDGLLPAFFSEISPRTQVPVKSTIAIGVLAAALAFFMD 377

  Fly   398 LSQLVNMMSIGTLLAYSMVASCVLMLRY-------------EVDDRRESRI-VANGRATGLE-QD 447
            ::||..|:|:|||:|::.||.|||:|||             .:.|..|||. ..|.....:| .|
plant   378 VAQLSEMVSVGTLMAFTAVAVCVLVLRYVPPDGVPLSSSSQTLSDTDESRAETENFLVDAIESSD 442

  Fly   448 RPCALWRRIFNLNGQTVPTK----QTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFD--G 506
            .|.        |..:|...:    :..:|..:|:.|..:..:..:...:  .|.|.:...|.  |
plant   443 SPL--------LGNETARDEKYFGKRRKIAAWSIALVCIGVLGLASAAS--AERLPSFPRFTICG 497

  Fly   507 IK--LVLGTIPLAVLLLVISRQPTSGVKLSFKVPLVPWLPGISILINIYLMIKLDILTWIRFSIW 569
            :.  ::||::.....:.....:...|.|..|..|.||:||.:.||||.||:|.:...||||..||
plant   498 VSAVILLGSLITLGYIDEDEERHNFGHKGGFLCPFVPYLPVLCILINTYLIINIGAGTWIRVLIW 562

  Fly   570 IAIGLAIFLAYGIRHSRLRQREQRNNSI 597
            :.||..|::.||..||.|      ||::
plant   563 LLIGSMIYIFYGRSHSLL------NNAV 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	196/599 (33%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617	24/49 (49%)
CAT4	NP_001154586.1	2A0303	4..579	CDD:273330	197/600 (33%)
CAT4	NP_001154586.1	AA_permease_C	528..578	CDD:290617	24/49 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	307	1.000	Domainoid score	I322
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20658
Inparanoid	1	1.050	352	1.000	Inparanoid score	I609
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D439017at2759
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm1003
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840